Alcohols

cytochrome P450 family 2 subfamily E member 1 ; Homo sapiens







227 Article(s)
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Pub. Year
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1 35204686 Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry. 2022 Jan 22 2
2 33197431 Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4. 2021 Feb 15 2
3 33675874 Alcohol-induced Hsp90 acetylation is a novel driver of liver sinusoidal endothelial dysfunction and alcohol-related liver disease. 2021 Aug 3
4 31987047 Relationship of ALDH2 rs671 and CYP2E1 rs2031920 with hepatocellular carcinoma susceptibility in East Asians: a meta-analysis. 2020 Jan 27 2
5 32080896 Glutamate Signaling in Alcohol-associated Fatty Liver: "Pas de Deux". 2020 Jul 2
6 32230811 Role of Alcohol Drinking in Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis. 2020 Mar 27 2
7 32738395 Alcohol-induced CYP2E1, mitochondrial dynamics and retrograde signaling in human hepatic 3D organoids. 2020 Nov 1 7
8 32821333 Oxidative stress in alcohol-related liver disease. 2020 Jul 27 1
9 33053940 Oxidative stress and glutamate excretion in alcoholic steatosis: Metabolic synapse between hepatocyte and stellate cell. 2020 Oct 2
10 33214856 Ethanol-induced CYP2E1 Expression is Reduced by Lauric Acid via PI3K Pathway in HepG2 Cells. 2020 Oct 2
11 30334271 CYP2E1 activity and children with obesity: possible confounding factors. 2019 Feb 2
12 30380359 Establishment of a p-nitrophenol oxidation-based assay for the analysis of CYP2E1 activity in intact hepatocytes in vitro. 2019 Mar 3
13 30582009 The role of cytochrome P450 2E1 on ethanol-mediated oxidative stress and HIV replication in human monocyte-derived macrophages. 2019 Mar 2
14 30667528 Microsomal Ethanol-Oxidizing System: Success Over 50 Years and an Encouraging Future. 2019 Mar 1
15 31024054 Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway. 2019 Apr 25 3
16 31423187 Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high-incidence area of northern China. 2019 Aug 4
17 31576541 Contributing Roles of CYP2E1 and Other Cytochrome P450 Isoforms in Alcohol-Related Tissue Injury and Carcinogenesis. 2019 1
18 29120493 Carcinogenic Etheno DNA Adducts in Alcoholic Liver Disease: Correlation with Cytochrome P-4502E1 and Fibrosis. 2018 Feb 3
19 29458168 Apoptosis of enterocytes and nitration of junctional complex proteins promote alcohol-induced gut leakiness and liver injury. 2018 Jul 2
20 29853304 Sasa quelpaertensis leaves ameliorate alcohol-induced liver injury by attenuating oxidative stress in HepG2 cells and mice. 2018 Jul 1
21 30362089 Glutathione and Transsulfuration in Alcohol-Associated Tissue Injury and Carcinogenesis. 2018 1
22 30362092 Chronic Ethanol Consumption and Generation of Etheno-DNA Adducts in Cancer-Prone Tissues. 2018 2
23 30424581 Alcoholic Liver Disease: Alcohol Metabolism, Cascade of Molecular Mechanisms, Cellular Targets, and Clinical Aspects. 2018 Nov 12 3
24 26278393 Role of CYP2E1 in Mitochondrial Dysfunction and Hepatic Injury by Alcohol and Non-Alcoholic Substances. 2017 2
25 27055685 Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells. 2017 Jan 1
26 28163821 The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain. 2017 2
27 28538665 Molecular Basis of Alcohol-Related Gastric and Colon Cancer. 2017 May 24 1
28 28805741 Alcohol and Cancer: Mechanisms and Therapies. 2017 Aug 14 2
29 28864499 Ethanol metabolism by alcohol dehydrogenase or cytochrome P450 2E1 differentially impairs hepatic protein trafficking and growth hormone signaling. 2017 Dec 1 6
30 28904078 Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences. 2017 Oct 10 1
31 28960346 CREB Protein Mediates Alcohol-Induced Circadian Disruption and Intestinal Permeability. 2017 Dec 3
32 28971616 Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors. 2017 Oct 2
33 29404441 The role of human cytochrome P450 2E1 in liver inflammation and fibrosis. 2017 Dec 2
34 29404485 Increased ethanol-inducible cytochrome P450-2E1 and cytochrome P450 isoforms in exosomes of alcohol-exposed rodents and patients with alcoholism through oxidative and endoplasmic reticulum stress. 2017 Sep 6
35 26415102 Systematic transcriptome analysis reveals elevated expression of alcohol-metabolizing genes in NAFLD livers. 2016 Mar 1
36 26755857 Optimal management for alcoholic liver disease: Conventional medications, natural therapy or combination? 2016 Jan 7 1
37 27007134 Moderate Alcohol Use and Insulin Action in Chronic Hepatitis C Infection. 2016 Aug 1
38 27916141 DNA damage in peripheral blood lymphocytes and association with polymorphisms in the promoter region of the CYP2E1 gene in alcoholics from Central Brazil. 2016 Dec 3
39 25427901 Alcohol and cancer: an overview with special emphasis on the role of acetaldehyde and cytochrome P450 2E1. 2015 3
40 25427918 The effect of alcohol on Sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC). 2015 1
41 25514903 Genetic variability in CYP2E1 and catalase gene among currently and formerly alcohol-dependent male subjects. 2015 Mar 1
42 26005678 The generation of carcinogenic etheno-DNA adducts in the liver of patients with nonalcoholic fatty liver disease. 2015 Apr 2
43 26045716 Genetic susceptibility in childhood acute leukaemias: a systematic review. 2015 1
44 26233911 Translational Implications of the Alcohol-Metabolizing Enzymes, Including Cytochrome P450-2E1, in Alcoholic and Nonalcoholic Liver Disease. 2015 4
45 26396584 Enhanced oxidative stress by alcohol use in HIV+ patients: possible involvement of cytochrome P450 2E1 and antioxidant enzymes. 2015 4
46 26497211 Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro. 2015 Dec 8 4
47 26501338 Autophagy Protects against CYP2E1/Chronic Ethanol-Induced Hepatotoxicity. 2015 Oct 16 1
48 26551085 Induction of CYP2E1 in non-alcoholic fatty liver diseases. 2015 Dec 2
49 24060752 Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis. 2014 Jan 1
50 24561005 Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity. 2014 Apr 6 1