| 1 |
35145060 | Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy. | 2022 Feb 10 |
1 |
| 2 |
35500453 | Short-term high-fat diet alters acetaminophen metabolism in healthy individuals. | 2022 Apr 30 |
1 |
| 3 |
35624743 | DDAH1 Protects against Acetaminophen-Induced Liver Hepatoxicity in Mice. | 2022 Apr 29 |
1 |
| 4 |
34440600 | The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity. | 2021 Aug 21 |
1 |
| 5 |
34951044 | Large paracetamol overdose - Higher dose NAC is NOT required. | 2021 Dec 23 |
1 |
| 6 |
31393259 | Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children. | 2020 |
2 |
| 7 |
31631733 | Evaluation of mRNA expression of drug-metabolizing enzymes in acetaminophen-induced hepatotoxicity using a three-dimensional hepatocyte culture system. | 2020 Jun |
1 |
| 8 |
32476096 | Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring. | 2020 Jun 1 |
3 |
| 9 |
32683859 | High-Selectivity Fluorescent Reporter toward Peroxynitrite in a Coexisting Nonalcoholic Fatty Liver and Drug-Induced Liver Diseases Model. | 2020 Aug 18 |
2 |
| 10 |
32762579 | Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review. | 2020 Dec |
2 |
| 11 |
32879799 | Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan. | 2020 |
1 |
| 12 |
30151903 | Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily-Dosing Model. | 2019 Jan |
3 |
| 13 |
30886645 | Human three-dimensional in vitro model of hepatic zonation to predict zonal hepatotoxicity. | 2019 |
1 |
| 14 |
31024054 | Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway. | 2019 Apr 25 |
3 |
| 15 |
31349598 | A Review of Bioinformatics Tools to Understand Acetaminophen-Alcohol Interaction. | 2019 Jul 25 |
1 |
| 16 |
29725998 | Comment on: "Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen". | 2018 Jul |
1 |
| 17 |
29736840 | Author's Reply to Reith: "Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen". | 2018 Jul |
1 |
| 18 |
30121710 | An insight into paracetamol and its metabolites using molecular docking and molecular dynamics simulation. | 2018 Aug 18 |
1 |
| 19 |
28438567 | A systematic evaluation of microRNAs in regulating human hepatic CYP2E1. | 2017 Aug 15 |
4 |
| 20 |
28627888 | Investigation of Drug-Induced Hepatotoxicity and Its Remediation Pathway with Reaction-Based Fluorescent Probes. | 2017 Jul 18 |
1 |
| 21 |
28663312 | Race, Gender, and Genetic Polymorphism Contribute to Variability in Acetaminophen Pharmacokinetics, Metabolism, and Protein-Adduct Concentrations in Healthy African-American and European-American Volunteers. | 2017 Sep |
1 |
| 22 |
28951593 | MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity. | 2017 Sep 26 |
2 |
| 23 |
28971616 | Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors. | 2017 Oct |
2 |
| 24 |
26739624 | A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen. | 2016 Feb 1 |
2 |
| 25 |
26818482 | Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen. | 2016 Jul |
3 |
| 26 |
26199425 | Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3'-Untranslated Region Affect the Regulation of CYP2E1 by miR-570. | 2015 Oct |
2 |
| 27 |
26225832 | Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures. | 2015 Oct 1 |
3 |
| 28 |
26607827 | Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome. | 2015 Nov 26 |
1 |
| 29 |
24458977 | Fennel and raspberry leaf as possible inhibitors of acetaminophen oxidation. | 2014 Oct |
2 |
| 30 |
24492462 | Evaluation of three-dimensional cultured HepG2 cells in a nano culture plate system: an in vitro human model of acetaminophen hepatotoxicity. | 2014 |
2 |
| 31 |
25228302 | The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes. | 2014 Dec |
1 |
| 32 |
25349782 | Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure. | 2014 |
2 |
| 33 |
23436315 | Effect of excipients on acetaminophen metabolism and its implications for prevention of liver injury. | 2013 Apr |
2 |
| 34 |
23728527 | Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity. | 2013 Aug |
1 |
| 35 |
22385180 | Molecular dynamics simulations of CYP2E1. | 2012 Mar |
1 |
| 36 |
22613176 | Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen. | 2012 Aug |
2 |
| 37 |
22939915 | Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo. | 2012 Oct 2 |
1 |
| 38 |
23032911 | Paracetamol and simvastatin: a potential interaction resulting in hepatotoxicity. | 2012 |
1 |
| 39 |
23107445 | Pharmacogenetic selection of transplanted human hepatocytes in immunocompetent rats. | 2012 Nov |
1 |
| 40 |
23166834 | Acetaminophen induces human neuroblastoma cell death through NFKB activation. | 2012 |
1 |
| 41 |
21130154 | Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen. | 2011 Mar |
6 |
| 42 |
27147854 | Does cytochrome P450 liver isoenzyme induction increase the risk of liver toxicity after paracetamol overdose? | 2011 |
2 |
| 43 |
20166895 | Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1. | 2010 Mar |
2 |
| 44 |
18751681 | Ruthenium red protects HepG2 cells overexpressing CYP2E1 against acetaminophen cytotoxicity. | 2009 Jan |
1 |
| 45 |
19219744 | Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes. | 2009 Jan |
1 |
| 46 |
19526678 | [DockingServer: molecular docking calculations online]. | 2009 |
2 |
| 47 |
18346862 | Interspecies differences in acetaminophen sensitivity of human, rat, and mouse primary hepatocytes. | 2008 Jun |
1 |
| 48 |
18379447 | Interaction of paracetamol in chronic alcoholic patients. Importance for odontologists. | 2008 Apr 1 |
1 |
| 49 |
18818195 | Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates. | 2008 Nov 28 |
1 |
| 50 |
17020953 | The 2006 Bernard B. Brodie Award Lecture. Cyp2e1. | 2007 Jan |
2 |