Title : Paracetamol and simvastatin: a potential interaction resulting in hepatotoxicity.

Pub. Date : 2012

PMID : 23032911






1 Functional Relationships(s)
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1 Paracetamol is metabolized by CYP enzymes (CYP2E1, 1A2, 2A6, 3A4) to a reactive metabolite, N-acetyl-p-benzoquinone-imine (NAPQI). Acetaminophen cytochrome P450 family 2 subfamily E member 1 Homo sapiens