Title : The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity.

Pub. Date : 2021 Aug 21

PMID : 34440600






1 Functional Relationships(s)
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1 By applying 3D culture methods, CYP2E1 mRNA levels could be elevated, but we failed to achieve a significant increase in hepatocyte function; hence, the 3D cultivation especially in APAP toxicity studies is not necessarily worth the complicated maintenance. Acetaminophen cytochrome P450 family 2 subfamily E member 1 Homo sapiens