Pub. Date : 2014
PMID : 24492462
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The NCP-cultured HepG2 cells showed higher expression of mRNA and protein levels of cytochrome P450 2E1, which metabolizes APAP to a toxic metabolite, APAP-cysteine adduct formation, and higher sensitivity against APAP-induced cell injury compared with conventionally cultured cells. | Acetaminophen | cytochrome P450 family 2 subfamily E member 1 | Homo sapiens |
2 | The NCP-cultured HepG2 cells showed higher expression of mRNA and protein levels of cytochrome P450 2E1, which metabolizes APAP to a toxic metabolite, APAP-cysteine adduct formation, and higher sensitivity against APAP-induced cell injury compared with conventionally cultured cells. | Acetaminophen | cytochrome P450 family 2 subfamily E member 1 | Homo sapiens |