Tetradecanoylphorbol Acetate

JunB proto-oncogene, AP-1 transcription factor subunit ; Homo sapiens







103 Article(s)
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1 33760219 Bruton's agammaglobulinemia tyrosine kinase (Btk) regulates TPA‑induced breast cancer cell invasion via PLCγ2/PKCβ/NF‑κB/AP‑1‑dependent matrix metalloproteinase‑9 activation. 2021 May 1
2 34093777 Triptolide inhibits matrix metalloproteinase-9 expression and invasion of breast cancer cells through the inhibition of NF-κB and AP-1 signaling pathways. 2021 Jul 1
3 34114342 Pro-inflammatory signals induce 20α-HSD expression in myometrial cells: A key mechanism for local progesterone withdrawal. 2021 Jul 1
4 29371085 (E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol attenuates PMA-induced inflammatory responses in human monocytic cells through PKCδ/JNK/AP-1 pathways. 2018 Apr 15 3
5 30133131 7-Methoxy-luteolin-8-C-β-6-deoxy-xylo-pyranos-3-uloside exactly (mLU8C-PU) isolated from Arthraxon hispidus inhibits migratory and invasive responses mediated via downregulation of MMP-9 and IL-8 expression in MCF-7 breast cancer cells. 2018 Nov 2
6 30466990 Orientin inhibits invasion by suppressing MMP-9 and IL-8 expression via the PKCα/ ERK/AP-1/STAT3-mediated signaling pathways in TPA-treated MCF-7 breast cancer cells. 2018 Nov 15 3
7 27538486 Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma. 2017 Mar 1
8 28927117 Salvia miltiorrhiza extract inhibits TPA-induced MMP-9 expression and invasion through the MAPK/AP-1 signaling pathway in human breast cancer MCF-7 cells. 2017 Sep 2
9 27035791 Gold-conjugated resveratrol nanoparticles attenuate the invasion and MMP-9 and COX-2 expression in breast cancer cells. 2016 Jun 3
10 24317440 A novel retinoic acid analog, 4-amino-2-trifluoromethyl-phenyl retinate, inhibits gastric cancer cell growth. 2014 Feb 2
11 25051397 Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: recruiting histone deacetylase and inhibiting activator protein 1 transcription factors. 2014 Oct 1
12 23151889 Surfactin suppresses TPA-induced breast cancer cell invasion through the inhibition of MMP-9 expression. 2013 Jan 2
13 23242121 Cis-guggulsterone inhibits the IKK/NF-κB pathway, whereas trans-guggulsterone inhibits MAPK/AP-1 in MCF‑7 breast cancer cells: guggulsterone regulates MMP‑9 expression in an isomer-specific manner. 2013 Feb 1
14 23288142 Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells. 2013 May 1
15 23615261 Sulforaphane controls TPA-induced MMP-9 expression through the NF-κB signaling pathway, but not AP-1, in MCF-7 breast cancer cells. 2013 Apr 1
16 23615401 Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells. 2013 Aug 3
17 20669087 Cancer chemopreventive activity of maslinic acid: suppression of COX-2 expression and inhibition of NF-κB and AP-1 activation in Raji cells. 2011 Jan 2
18 20959602 Dynamic combinatorial interactions of RUNX1 and cooperating partners regulates megakaryocytic differentiation in cell line models. 2011 Jan 6 1
19 21129776 Epigenetic mechanisms regulate ΔNP73 promoter function in human tonsil B cells. 2011 Jan 1
20 21246637 Evodiamine inhibits 12-O-tetradecanoylphorbol-13-acetate-induced activator protein 1 transactivation and cell transformation in human hepatocytes. 2011 Jul 6
21 21262201 Dihydroavenanthramide D inhibits human breast cancer cell invasion through suppression of MMP-9 expression. 2011 Feb 25 3
22 21381080 Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells. 2011 Jul 2
23 20053986 Heterodimerization with different Jun proteins controls c-Fos intranuclear dynamics and distribution. 2010 Feb 26 1
24 20082219 Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expression. 2010 Feb 28 1
25 20138977 The inhibitory effect of hesperidin on tumor cell invasiveness occurs via suppression of activator protein 1 and nuclear factor-kappaB in human hepatocellular carcinoma cells. 2010 Apr 15 1
26 20550117 Anti-invasive effect of a rare mushroom, Ganoderma colossum , on human hepatoma cells. 2010 Jul 14 2
27 18992303 Prolonged high glucose suppresses phorbol 12-myristate 13-acetate and ionomycin-induced interleukin-2 mRNA expression in Jurkat cells. 2009 Jan 1 2
28 19420016 Kalopanaxsaponin A inhibits PMA-induced invasion by reducing matrix metalloproteinase-9 via PI3K/Akt- and PKCdelta-mediated signaling in MCF-7 human breast cancer cells. 2009 Jul 4
29 19447859 Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells. 2009 Jul 3
30 18245498 Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine. 2008 Feb 1 1
31 17114644 Ascofuranone suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms. 2007 May 3
32 17207890 Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells. 2007 May 2
33 17394101 Antioxidant activity of Vaccinium stamineum: exhibition of anticancer capability in human lung and leukemia cells. 2007 May 2
34 17438848 [The role of protein kinase C and activator protein-1 signal cascade in the regulation of expression of interleukin-5 in T lymphocyte of allergic rhinitis]. 2007 Jan 1
35 16267831 Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappaB, but not c-Jun N-terminal kinase and activated protein-1. 2006 Jan 1
36 15790882 An involucrin promoter AP1 transcription factor binding site is required for expression of involucrin in the corneal epithelium in vivo. 2005 Apr 6
37 15797241 Repression of 5-aminolevulinate synthase gene by the potent tumor promoter, TPA, involves multiple signal transduction pathways. 2005 Apr 15 4
38 15878157 The role of epidermal growth factor receptor in ethanol-mediated inhibition of activator protein-1 transactivation. 2005 Jun 15 2
39 14673171 Recruitment of SWI/SNF to the human immunodeficiency virus type 1 promoter. 2004 Jan 1
40 15037572 Regulation of involucrin expression in normal human corneal epithelial cells: a role for activator protein one. 2004 Apr 4
41 15329596 Sevoflurane inhibits phorbol-myristate-acetate-induced activator protein-1 activation in human T lymphocytes in vitro: potential role of the p38-stress kinase pathway. 2004 Sep 2
42 15465640 Glycoprotein isolated from Solanum nigrum L. inhibits the DNA-binding activities of NF-kappaB and AP-1, and increases the production of nitric oxide in TPA-stimulated MCF-7 cells. 2004 Dec 1
43 15627897 Activation of activator protein 1 and extracellular signal-regulated kinases in human hepatocellular transformation. 2004 Sep-Dec 11
44 15666830 On the control of the hCYP11B2 gene expressing cytochrome P450 aldosterone synthase. 2004 Nov 2
45 12592382 ERK signaling pathway is involved in p15INK4b/p16INK4a expression and HepG2 growth inhibition triggered by TPA and Saikosaponin a. 2003 Feb 20 1
46 14627504 Resveratrol inhibits matrix metalloproteinase-9 transcription in U937 cells. 2003 Nov 1
47 11751871 Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes. 2002 Feb 22 1
48 11861377 Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells. 2002 Feb 15 1
49 11948401 AP-1 transrepressing retinoic acid does not deplete coactivators or AP-1 monomers but may target specific Jun or Fos containing dimers. 2002 Mar 28 1
50 12009305 Anticancer effect of retinoic acid via AP-1 activity repression is mediated by retinoic acid receptor alpha and beta in gastric cancer cells. 2002 Sep 1