Title : Cis-guggulsterone inhibits the IKK/NF-κB pathway, whereas trans-guggulsterone inhibits MAPK/AP-1 in MCF‑7 breast cancer cells: guggulsterone regulates MMP‑9 expression in an isomer-specific manner.

Pub. Date : 2013 Feb

PMID : 23242121






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Cis-guggulsterone inhibited TPA-induced MMP expression by blocking IkappaB kinase (IKK)/NF-kappaB signaling, whereas trans-guggulsterone blocked mitogen-activated protein kinase (MAPK)/AP-1 signaling. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens