Pub. Date : 2018 Nov 15
PMID : 30466990
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Orientin inhibits invasion by suppressing MMP-9 and IL-8 expression via the PKCalpha/ ERK/AP-1/STAT3-mediated signaling pathways in TPA-treated MCF-7 breast cancer cells. | Tetradecanoylphorbol Acetate | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | TPA-induced membrane translocation of protein kinase C alpha (PKCalpha), phosphorylation of extracellular signal regulated kinase (ERK), and nuclear translocations of activator protein-1 (AP-1) and signal transducer and activator of transcription 3 (STAT3) were downregulated by orientin. | Tetradecanoylphorbol Acetate | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | TPA-induced membrane translocation of protein kinase C alpha (PKCalpha), phosphorylation of extracellular signal regulated kinase (ERK), and nuclear translocations of activator protein-1 (AP-1) and signal transducer and activator of transcription 3 (STAT3) were downregulated by orientin. | Tetradecanoylphorbol Acetate | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |