Pub. Date : 2004 Nov
PMID : 15666830
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TPA but not AII increased the level of the transcription factor JunB in nuclear extracts and the increase was partially abolished by the MEK1 inhibitor PD98059. | Tetradecanoylphorbol Acetate | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | Taken together these results suggest that TPA inhibits the AII-dependent activation of CYP11B2 via the p44/42 MAPK signaling pathway leading to an increase of the level of nuclear JunB. | Tetradecanoylphorbol Acetate | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |