D-serine

serine racemase ; Homo sapiens







104 Article(s)
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1 34806751 Commentary on "Urinary L-erythro-β-hydroxyasparagine - a novel serine racemase inhibitor and substrate of the Zn2+-dependent D-serine dehydratase". 2021 Nov 22 1
2 34874398 Commentary on Urinary l-erythro-β-hydroxyasparagine: a novel serine racemase inhibitor and substrate of the Zn2+-dependent d-serine dehydratase. 2021 Dec 22 1
3 30918891 Human Serine Racemase: Key Residues/Active Site Motifs and Their Relation to Enzyme Function. 2019 2
4 29025687 Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning. 2018 Feb 1 2
5 29277459 Design, synthesis, and evaluation of novel inhibitors for wild-type human serine racemase. 2018 Feb 1 2
6 29363864 SRR intronic variation inhibits expression of its neighbouring SMG6 gene and protects against temporal lobe epilepsy. 2018 Mar 2
7 29410194 Human serine racemase is nitrosylated at multiple sites. 2018 Jul 1
8 29413526 The Neurobiology of d-Serine Signaling. 2018 1
9 29566294 Inflammatory cytokine-mediated induction of serine racemase in atopic dermatitis. 2018 Jun 2
10 30093356 Chronic d-serine supplementation impairs insulin secretion. 2018 Oct 1
11 30546256 Peripheral Biomarker for Vascular Disorders. 2018 5
12 30555832 Changes in Serine Racemase-Dependent Modulation of NMDA Receptor: Impact on Physiological and Pathological Brain Aging. 2018 2
13 30687716 The Energy Landscape of Human Serine Racemase. 2018 2
14 27585868 Novel role of serine racemase in anti-apoptosis and metabolism. 2017 Jan 1
15 28089597 Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form. 2017 Apr 1
16 28560262 Decreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patients. 2017 1
17 28696262 Human serine racemase structure/activity relationship studies provide mechanistic insight and point to position 84 as a hot spot for β-elimination function. 2017 Aug 25 1
18 26133542 Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target. 2016 Aug 2
19 26851299 Nuclear compartmentalization of serine racemase regulates d-serine production. IMPLICATIONS FOR N-METHYL-d-ASPARTATE (NMDA) RECEPTOR ACTIVATION. 2016 Feb 5 1
20 26941605 D-Serine and Serine Racemase Are Associated with PSD-95 and Glutamatergic Synapse Stability. 2016 10
21 26954593 History of the Concept of Disconnectivity in Schizophrenia. 2016 Mar-Apr 1
22 27387750 Serine racemase is involved in d-aspartate biosynthesis. 2016 Dec 2
23 27493223 Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives. 2016 Oct 15 2
24 27742076 The Rise and Fall of the d-Serine-Mediated Gliotransmission Hypothesis. 2016 Nov 4
25 25331425 Regulation of human serine racemase activity and dynamics by halides, ATP and malonate. 2015 Jan 1
26 25462239 Malonate-based inhibitors of mammalian serine racemase: kinetic characterization and structure-based computational study. 2015 Jan 7 1
27 25493718 Understanding the reaction mechanism and intermediate stabilization in mammalian serine racemase using multiscale quantum-classical simulations. 2015 Jan 20 5
28 25666758 Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma. 2015 Dec 1
29 25870284 Glycolytic flux controls D-serine synthesis through glyceraldehyde-3-phosphate dehydrogenase in astrocytes. 2015 Apr 28 5
30 26283510 Expanding the chemical space of human serine racemase inhibitors. 2015 Oct 1 1
31 26553873 Nuclear Compartmentalization of Serine Racemase Regulates D-Serine Production: IMPLICATIONS FOR N-METHYL-D-ASPARTATE (NMDA) RECEPTOR ACTIVATION. 2015 Dec 25 6
32 24237903 The degradation (by distinct pathways) of human D-amino acid oxidase and its interacting partner pLG72--two key proteins in D-serine catabolism in the brain. 2014 Feb 1
33 24436034 D-serine and serine racemase are localized to neurons in the adult mouse and human forebrain. 2014 Apr 3
34 24795622 Serine racemase: a key player in apoptosis and necrosis. 2014 2
35 24795623 The role of D-serine and glycine as co-agonists of NMDA receptors in motor neuron degeneration and amyotrophic lateral sclerosis (ALS). 2014 1
36 25066953 In silico and pharmacological screenings identify novel serine racemase inhibitors. 2014 Aug 15 2
37 25083578 The postnatal development of D-serine in the retinas of two mouse strains, including a mutant mouse with a deficiency in D-amino acid oxidase and a serine racemase knockout mouse. 2014 Sep 17 2
38 25164819 Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk. 2014 Oct 24 4
39 25336657 FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. 2014 Dec 5 3
40 23116391 D-amino acid oxidase inhibitors as a novel class of drugs for schizophrenia therapy. 2013 1
41 23630460 D-serine as a gliotransmitter and its roles in brain development and disease. 2013 1
42 23747871 Serine racemase: a key player in neuron activity and in neuropathologies. 2013 Jun 1 1
43 23773062 Serine racemase as a prime target for age-related memory deficits. 2013 Jun 1
44 23992455 ATP binding to human serine racemase is cooperative and modulated by glycine. 2013 Nov 1
45 24256252 The serine shuttle between glia and neurons: implications for neurotransmission and neurodegeneration. 2013 Dec 1
46 24256253 D-Serine metabolism: new insights into the modulation of D-amino acid oxidase activity. 2013 Dec 1
47 21956576 Preparation and assay of recombinant serine racemase. 2012 1
48 22037294 Capillary electrophoresis-laser-induced fluorescence (CE-LIF) assay for measurement of intracellular D-serine and serine racemase activity. 2012 Feb 15 1
49 22311068 Metal ion dependency of serine racemase from Dictyostelium discoideum. 2012 Oct 3
50 22354542 Cross-linking of serine racemase dimer by reactive oxygen species and reactive nitrogen species. 2012 Jun 2