Pub. Date : 2012 Oct
PMID : 22311068
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | D-Serine is known to act as an endogenous co-agonist of the N-methyl-D-aspartate receptor in the mammalian brain and is endogenously synthesized from L-serine by a pyridoxal 5"-phosphate-dependent enzyme, serine racemase. | D-serine | serine racemase | Homo sapiens |
| 2 | Though the soil-living mycetozoa Dictyostelium discoideum possesses no genes homologous to that of NMDA receptor, it contains genes encoding putative proteins relating to the D-serine metabolism, such as serine racemase, D-amino acid oxidase, and D-serine dehydratase. | D-serine | serine racemase | Homo sapiens |
| 3 | As part of the elucidation of the role of D-serine in D. discoideum, we cloned, overexpressed, and examined the properties of the putative serine racemase exhibiting 46% amino acid sequence similarity with the human enzyme. | D-serine | serine racemase | Homo sapiens |