D-serine

serine racemase ; Homo sapiens







104 Article(s)
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51 22507034 Contribution of serine racemase/d-serine pathway to neuronal apoptosis. 2012 Aug 1
52 23112234 Modulating the function of human serine racemase and human serine dehydratase by protein engineering. 2012 Nov 1
53 21224019 Serine racemase and the serine shuttle between neurons and astrocytes. 2011 Nov 4
54 21291385 Inhibition of human serine racemase, an emerging target for medicinal chemistry. 2011 Jun 2
55 21392888 Glycine inhibitory dysfunction turns touch into pain through astrocyte-derived D-serine. 2011 Jun 1
56 21655447 Eph signaling regulates gliotransmitter release. 2011 Mar 1
57 21886585 Association study of serine racemase gene with methamphetamine psychosis. 2011 Mar 2
58 27466949 Addressing the Conformational Flexibility of Serine Racemase by Combining Targeted Molecular Dynamics, Conformational Sampling and Docking Studies. 2011 Apr 18 2
59 20091774 D-Serine metabolism in C6 glioma cells: Involvement of alanine-serine-cysteine transporter (ASCT2) and serine racemase (SRR) but not D-amino acid oxidase (DAO). 2010 Jun 6
60 20106978 The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. 2010 Apr 23 2
61 20417696 N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: the final common pathway on the road to schizophrenia? 2010 Sep 30 1
62 20623543 Potential roles of D-serine and serine racemase in experimental temporal lobe epilepsy. 2010 Aug 15 1
63 20966073 Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain. 2010 Dec 31 1
64 21106840 EphrinBs regulate D-serine synthesis and release in astrocytes. 2010 Nov 24 1
65 18812225 Recombinant human serine racemase: enzymologic characterization and comparison with its mouse ortholog. 2009 Jan 2
66 19155267 Serine racemase with catalytically active lysinoalanyl residue. 2009 Apr 1
67 19193859 Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition. 2009 Feb 24 3
68 19640845 Crystal structure of a homolog of mammalian serine racemase from Schizosaccharomyces pombe. 2009 Sep 18 1
69 19791805 Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor. 2009 Oct 8 1
70 20021361 Dual cross-talk between nitric oxide and D-serine in astrocytes and neurons in the brain. 2009 Dec 1
71 18564178 D-amino acids in the brain: the biochemistry of brain serine racemase. 2008 Jul 1
72 17156977 A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia. 2007 Feb 1
73 17254537 Simultaneous measurement of D-serine dehydratase and d-amino acid oxidase activities by the detection of 2-oxo-acid formation with reverse-phase high-performance liquid chromatography. 2007 Mar 1 1
74 17293453 Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation. 2007 Feb 20 3
75 17627481 Induction of serine racemase expression and D-serine release from microglia by secreted amyloid precursor protein (sAPP). 2007 Jul 1
76 17663143 [Role of D-serine in the mammalian brain]. 2007 Jul 2
77 17880399 d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia. 2007 Sep 2
78 16182447 Regulation of serine racemase activity by D-serine and nitric oxide in human glioblastoma cells. 2006 Jan 9 6
79 16298487 Mutual regulation between serine and nitric oxide metabolism in human glioblastoma cells. 2006 Feb 20 3
80 16314870 Serine racemase binds to PICK1: potential relevance to schizophrenia. 2006 Feb 2
81 16551623 Neuron-derived D-serine release provides a novel means to activate N-methyl-D-aspartate receptors. 2006 May 19 1
82 16714286 Modulation of D-serine levels via ubiquitin-dependent proteasomal degradation of serine racemase. 2006 Jul 21 3
83 16721908 Capillary electrophoresis method for determination of D-serine and its application for monitoring of serine racemase activity. 2006 Jul 3
84 16837850 Serine racemase protein expression in cortex and hippocampus in schizophrenia. 2006 Jul 31 1
85 17006901 Molecular determinants of D-serine-mediated gliotransmission: from release to function. 2006 Nov 15 2
86 15536068 Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity. 2005 Jan 21 4
87 15953485 Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels. 2005 Jun 15 5
88 15193426 Characterization and localization of a human serine racemase. 2004 Jun 18 3
89 15252817 D-Serine as a glial modulator of nerve cells. 2004 Aug 15 1
90 15285800 Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide. 2004 Apr 20 1
91 15306409 The N-methyl D-aspartate receptor glycine site and D-serine metabolism: an evolutionary perspective. 2004 Jun 29 2
92 15681805 Induction of serine racemase by inflammatory stimuli is dependent on AP-1. 2004 Dec 2
93 16543946 D-Serine as a putative glial neurotransmitter. 2004 Aug 2
94 12796220 Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. 2003 Jun 2
95 11864625 Glial transport of the neuromodulator D-serine. 2002 Mar 8 1
96 12021263 Direct calcium binding results in activation of brain serine racemase. 2002 Aug 2 2
97 12176074 Neurobiology through the looking-glass: D-serine as a new glial-derived transmitter. 2002 Nov 1
98 12393813 Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. 2002 Oct 29 6
99 11309496 A new strategy to decrease N-methyl-D-aspartate (NMDA) receptor coactivation: inhibition of D-serine synthesis by converting serine racemase into an eliminase. 2001 Apr 24 2
100 10781100 D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. 2000 Apr 25 1