Pub. Date : 2015 Jan 20
PMID : 25493718
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Serine racemase (SerR) is a pyridoxal-5"-phosphate (PLP)-dependent enzyme catalyzing the racemization of l-Ser to d-Ser. | D-serine | serine racemase | Homo sapiens |
| 2 | Serine racemase (SerR) is a pyridoxal-5"-phosphate (PLP)-dependent enzyme catalyzing the racemization of l-Ser to d-Ser. | D-serine | serine racemase | Homo sapiens |
| 3 | In mammals, d-Ser is an endogenous coagonist required for the activation of N-methyl-d-aspartate receptors (NMDARs), thus making SerR a promising pharmaceutical target. | D-serine | serine racemase | Homo sapiens |
| 4 | In addition to a deeper understanding of the racemization mechanism in SerR, based on our simulations we propose specific mutations, which might shift the SerR equilibrium in favor of either l-Ser or d-Ser. | D-serine | serine racemase | Homo sapiens |
| 5 | In addition to a deeper understanding of the racemization mechanism in SerR, based on our simulations we propose specific mutations, which might shift the SerR equilibrium in favor of either l-Ser or d-Ser. | D-serine | serine racemase | Homo sapiens |