Title : FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine.

Pub. Date : 2014 Dec 5

PMID : 25336657






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 d-Serine is synthesized from l-serine by serine racemase (SR), a brain-enriched enzyme. D-serine serine racemase Homo sapiens
2 d-Serine is synthesized from l-serine by serine racemase (SR), a brain-enriched enzyme. D-serine serine racemase Homo sapiens
3 We now demonstrate that the F-box only protein 22 (FBXO22) interacts with SR and is required for optimal d-serine synthesis in cells. D-serine serine racemase Homo sapiens