Reactive Oxygen Species

Rac family small GTPase 1 ; Rattus norvegicus







35 Article(s)
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1 34597250 The role of small GTPase Rac1 in ionizing radiation-induced testicular damage. 2022 2
2 35574363 Inhibition of (Pro)renin Receptor-Mediated Oxidative Stress Alleviates Doxorubicin-Induced Heart Failure. 2022 1
3 33081375 Y-27632 Induces Neurite Outgrowth by Activating the NOX1-Mediated AKT and PAK1 Phosphorylation Cascades in PC12 Cells. 2020 Oct 16 1
4 29494287 Resveratrol regulates blood pressure by enhancing AMPK signaling to downregulate a Rac1-derived NADPH oxidase in the central nervous system. 2018 Jul 1 5
5 30013448 Rac1 promotes the survival of H9c2 cells during serum deficiency targeting JNK/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways. 2018 2
6 28132913 Nebivolol prevents ethanol-induced reactive oxygen species generation and lipoperoxidation in the rat kidney by regulating NADPH oxidase activation and expression. 2017 Mar 15 1
7 28338001 Renin-angiotensin system acting on reactive oxygen species in paraventricular nucleus induces sympathetic activation via AT1R/PKCγ/Rac1 pathway in salt-induced hypertension. 2017 Mar 24 2
8 25981400 Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury. 2016 Jan 1
9 26824355 The GTPase ARF6 Controls ROS Production to Mediate Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation. 2016 1
10 27035426 Farnesyl pyrophosphate synthase inhibitor, ibandronate, improves endothelial function in spontaneously hypertensive rats. 2016 May 1
11 27138844 Resveratrol Inhibition of Rac1-Derived Reactive Oxygen Species by AMPK Decreases Blood Pressure in a Fructose-Induced Rat Model of Hypertension. 2016 May 3 2
12 27159442 miR-124 Regulates Amadori-Glycated Albumin-Induced Retinal Microglial Activation and Inflammation by Targeting Rac1. 2016 May 1 1
13 24872317 RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species. 2014 Jul 15 1
14 23153365 Activation of Rac1-dependent redox signaling is critically involved in staurosporine-induced neurite outgrowth in PC12 cells. 2013 Feb 1
15 22114025 NADPH oxidase-mediated Rac1 GTP activity is necessary for nongenomic actions of the mineralocorticoid receptor in the CA1 region of the rat hippocampus. 2012 Feb 15 1
16 22140048 Cooperative interaction between reactive oxygen species and Ca2+ signals contributes to angiotensin II-induced hypertrophy in adult rat cardiomyocytes. 2012 Feb 15 1
17 21195169 Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death. 2011 Mar 1 2
18 21228337 Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation. 2011 Mar 1
19 21911753 Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet. 2011 Nov 1
20 19854265 Puerarin attenuates high-glucose-and diabetes-induced vascular smooth muscle cell proliferation by blocking PKCbeta2/Rac1-dependent signaling. 2010 Feb 15 1
21 20628008 Preventive effects of pravastatin on thrombin-triggered vascular responses via Akt/eNOS and RhoA/Rac1 pathways in vivo. 2010 Dec 1 2
22 20830300 Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat. 2010 Sep 7 2
23 17950325 Mycophenolic acid inhibits cell proliferation and extracellular matrix synthesis in rat vascular smooth muscle cells through direct and indirect inhibition of cellular reactive oxygen species. 2008 Nov 1
24 18567639 Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells. 2008 Nov 1 3
25 18650132 Role of reactive oxygen species in brainstem in neural mechanisms of hypertension. 2008 Nov 3 1
26 18773185 Mechanisms of angiotensin II signaling on cytoskeleton of podocytes. 2008 Dec 1
27 17515454 Inhibition of Rac1-derived reactive oxygen species in nucleus tractus solitarius decreases blood pressure and heart rate in stroke-prone spontaneously hypertensive rats. 2007 Jul 4
28 16357365 Hyperoxia-induced reactive oxygen species formation in pulmonary capillary endothelial cells in situ. 2006 Apr 1
29 16624288 ROS up-regulation mediates Ras-induced changes of cell morphology and motility. 2006 Jul 1 2
30 16698001 Association of RhoGDIalpha with Rac1 GTPase mediates free radical production during myocardial hypertrophy. 2006 Jul 15 2
31 15217908 IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation. 2004 Aug 6 2
32 14555937 Inactivation of the small GTPase Rac1 protects the liver from ischemia/reperfusion injury in the rat. 2003 Sep 1
33 11179461 Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: involvement of angiotensin AT1 receptor expression and Rac1 GTPase. 2001 Mar 1
34 11748350 Inhibition of rac1 reduces PDGF-induced reactive oxygen species and proliferation in vascular smooth muscle cells. 2001 Dec 3
35 10788420 Nerve growth factor-induced neuronal differentiation requires generation of Rac1-regulated reactive oxygen species. 2000 May 5 3