Title : Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death.

Pub. Date : 2011 Mar 1

PMID : 21195169






2 Functional Relationships(s)
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1 Here we show that Cd induces the generation of reactive oxygen species (ROS) by upregulating the expression of NADPH oxidase 2 and its regulatory proteins (p22(phox), p67(phox), p40(phox), p47(phox), and Rac1) in PC12 and SH-SY5Y cells. Reactive Oxygen Species Rac family small GTPase 1 Rattus norvegicus
2 Here we show that Cd induces the generation of reactive oxygen species (ROS) by upregulating the expression of NADPH oxidase 2 and its regulatory proteins (p22(phox), p67(phox), p40(phox), p47(phox), and Rac1) in PC12 and SH-SY5Y cells. Reactive Oxygen Species Rac family small GTPase 1 Rattus norvegicus