cytochrome P450, family 7, subfamily b, polypeptide 1 ; Mus musculus






47 Article(s)
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1 8530364 A novel cytochrome P450 expressed primarily in brain. J Biol Chem 1995 Dec 15 2
2 8663430 Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase. J Biol Chem 1996 Jul 26 3
3 10748047 Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol. J Biol Chem 2000 Jun 2 5
4 10748048 Disruption of the oxysterol 7alpha-hydroxylase gene in mice. J Biol Chem 2000 Jun 2 6
5 10845871 Cafestol increases serum cholesterol levels in apolipoprotein E*3-Leiden transgenic mice by suppression of bile acid synthesis. Arterioscler Thromb Vasc Biol 2000 Jun 1
6 12370428 An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth. Proc Natl Acad Sci U S A 2002 Oct 15 3
7 12735108 Gene expression profiles associated with inflammation, fibrosis, and cholestasis in mouse liver after griseofulvin. EHP Toxicogenomics 2003 Jan 2
8 14599559 Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1alpha)-deficient mice. Biochem Pharmacol 2003 Nov 15 2
9 14691202 Toxicogenomic analysis of aberrant gene expression in liver tumors and nontumorous livers of adult mice exposed in utero to inorganic arsenic. Toxicol Sci 2004 Feb 1
10 15710898 Early onset of puberty and early ovarian failure in CYP7B1 knockout mice. Proc Natl Acad Sci U S A 2005 Feb 22 8
11 16264197 Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4alpha. J Lipid Res 2006 Jan 1
12 16368122 Transplacental arsenic plus postnatal 12-O-teradecanoyl phorbol-13-acetate exposures associated with hepatocarcinogenesis induce similar aberrant gene expression patterns in male and female mouse liver. Toxicol Appl Pharmacol 2006 Jun 15 2
13 16606610 Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity. J Biol Chem 2006 Jun 16 1
14 17441966 Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice. Cancer Sci 2007 Jun 1
15 17873880 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. Nat Med 2007 Oct 1
16 18055760 Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3). Mol Pharmacol 2008 Mar 6
17 18535165 The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic gene regulation. Exp Biol Med (Maywood) 2008 Oct 2
18 18587407 Hepatic insulin resistance directly promotes formation of cholesterol gallstones. Nat Med 2008 Jul 1
19 18925944 Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT. BMC Genomics 2008 Oct 16 1
20 18982005 Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain. Mol Psychiatry 2009 Feb 1
21 19732851 CYP7B1-mediated metabolism of 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol): a novel pathway for potential regulation of the cellular levels of androgens and neurosteroids. Biochim Biophys Acta 2009 Dec 1
22 21796211 Oxysterols direct B-cell migration through EBI2. Nature 2011 Jul 27 5
23 22207087 Influence of depleted uranium on hepatic cholesterol metabolism in apolipoprotein E-deficient mice. J Steroid Biochem Mol Biol 2012 Apr 1
24 22927828 Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting. PLoS Genet 2012 Aug 1
25 24832732 24S,25-Epoxycholesterol in mouse and rat brain. Biochem Biophys Res Commun 2014 Jun 27 2
26 24954418 The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha. Cell Metab 2014 Jul 1 3
27 25849728 CYP7B1 Enzyme Deletion Impairs Reproductive Behaviors in Male Mice. Endocrinology 2015 Jun 4
28 27351453 G-protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis in mice. Hepatology 2017 Mar 1
29 28604703 Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis. Nat Med 2017 Jul 1
30 28720595 Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses. Endocr Connect 2017 Oct 2
31 28928671 Aerobic Exercise Training Selectively Changes Oxysterol Levels and Metabolism Reducing Cholesterol Accumulation in the Aorta of Dyslipidemic Mice. Front Physiol 2017 2
32 29172112 Cholesterol-lowering effects of dietary pomegranate extract and inulin in mice fed an obesogenic diet. J Nutr Biochem 2018 Feb 1
33 29674392 Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease. EMBO Mol Med 2018 May 1
34 30630288 Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice. Biomol Ther (Seoul) 2019 Mar 1 1
35 30728500 The CH25H-CYP7B1-RORα axis of cholesterol metabolism regulates osteoarthritis. Nature 2019 Feb 3
36 31013940 Mining for Oxysterols in <i>Cyp7b1<sup>-/-</sup></i> Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5. Biomolecules 2019 Apr 13 2
37 31384531 Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters. Acta Pharm Sin B 2019 Jul 8
38 31852219 MicroRNA-144 Silencing Protects Against Atherosclerosis in Male, but Not Female Mice. Arterioscler Thromb Vasc Biol 2020 Feb 4
39 32745909 Quantitative proteomic analysis of the liver reveals antidepressant potential protein targets of Sinisan in a mouse CUMS model of depression. Biomed Pharmacother 2020 Oct 1
40 33008924 Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition. J Lipid Res 2020 Dec 4
41 33083728 Hippocampal 7α-Hydroxylated Neurosteroids Are Raised by Training and Bolster Remote Spatial Memory with Increase of the Spine Densities. iScience 2020 Oct 23 14
42 33154041 Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obeticholic Acid Is Controlled by Constitutive Androstane Receptor through Intestinal Maturation. Drug Metab Dispos 2021 Jan 1
43 34563664 Deficiency of coiled-coil domain containing 80 increases plasma cholesterol by decreasing fecal sterols excretion in hypercholesterolemic mice. J Nutr Biochem 2021 Dec 2
44 34685636 Oxysterol 7-α Hydroxylase (CYP7B1) Attenuates Metabolic-Associated Fatty Liver Disease in Mice at Thermoneutrality. Cells 2021 Oct 5 2
45 34970143 Ilexsaponin A<sub>1</sub> Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism in Mice. Front Pharmacol 2021 2
46 35303091 A Blunted GPR183/Oxysterol Axis During Dysglycemia Results in Delayed Recruitment of Macrophages to the Lung During Mycobacterium tuberculosis Infection. J Infect Dis 2022 Jun 15 1
47 35478959 Cold-Induced Lipoprotein Clearance in <i>Cyp7b1</i>-Deficient Mice. Front Cell Dev Biol 2022 5