Title : Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis.

Pub. Date : 2017 Jul

PMID : 28604703






1 Functional Relationships(s)
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1 This process is dependent on hepatic induction of cytochrome P450, family 7, subfamily b, polypeptide 1 (CYP7B1) and results in increased plasma levels, as well as fecal excretion, of bile acids that is accompanied by distinct changes in gut microbiota and increased heat production. Bile Acids and Salts cytochrome P450, family 7, subfamily b, polypeptide 1 Mus musculus