| Protein Name | cytochrome P450, family 7, subfamily b, polypeptide 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13123 |
| Gene Symbol | Cyp7b1 |
| UniProt | Q60991 (CP7B1_MOUSE), Q3USU4 (Q3USU4_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
37
Total Number of Articles : 47 |
Description |
cytochrome P450, family 7, subfamily b, polypeptide 1 |
| Gene Summary |
Predicted to enable steroid hydroxylase activity. Involved in B cell chemotaxis and bile acid biosynthetic process. Acts upstream of or within negative regulation of intracellular estrogen receptor signaling pathway; positive regulation of epithelial cell proliferation; and prostate gland epithelium morphogenesis. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and sensory organ. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 3 and hereditary spastic paraplegia 5A. Orthologous to human CYP7B1 (cytochrome P450 family 7 subfamily B member 1). [provided by Alliance of Genome Resources, Jul 2025] |
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