Title : An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth.

Pub. Date : 2002 Oct 15

PMID : 12370428






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Because CYP7B1 represents the major pathway for inactivating 3betaAdiol in the prostate, we suggest that ERbeta, 3betaAdiol, and CYP7B1 are the components of a pathway that regulates growth of the rodent ventral prostate. Androstane-3,17-diol cytochrome P450, family 7, subfamily b, polypeptide 1 Mus musculus
2 In this pathway, ERbeta is an antiproliferative receptor, 3betaAdiol is an ERbeta ligand, and CYP7B1 is the enzyme that regulates ERbeta function by regulating the level of 3betaAdiol. Androstane-3,17-diol cytochrome P450, family 7, subfamily b, polypeptide 1 Mus musculus
3 In this pathway, ERbeta is an antiproliferative receptor, 3betaAdiol is an ERbeta ligand, and CYP7B1 is the enzyme that regulates ERbeta function by regulating the level of 3betaAdiol. Androstane-3,17-diol cytochrome P450, family 7, subfamily b, polypeptide 1 Mus musculus