Pub. Date : 2020 Feb
PMID : 31852219
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | As a molecular mechanism, we identify the oxysterol metabolizing enzyme CYP7B1 (cytochrome P450 enzyme 7B1) as a miR-144 regulated gene in male, but not female mice. | arthrofactin | cytochrome P450, family 7, subfamily b, polypeptide 1 | Mus musculus |
2 | As a molecular mechanism, we identify the oxysterol metabolizing enzyme CYP7B1 (cytochrome P450 enzyme 7B1) as a miR-144 regulated gene in male, but not female mice. | arthrofactin | cytochrome P450, family 7, subfamily b, polypeptide 1 | Mus musculus |
3 | Consistent with miR-144-dependent changes in CYP7B1 activity, we show decreased levels of 27-hydroxycholesterol, a known proatherogenic sterol and the endogenous substrate for CYP7B1 in male, but not female mice. | Sterols | cytochrome P450, family 7, subfamily b, polypeptide 1 | Mus musculus |
4 | Consistent with miR-144-dependent changes in CYP7B1 activity, we show decreased levels of 27-hydroxycholesterol, a known proatherogenic sterol and the endogenous substrate for CYP7B1 in male, but not female mice. | Sterols | cytochrome P450, family 7, subfamily b, polypeptide 1 | Mus musculus |