| 1 | 14730349 | Crystal structure of MO25 alpha in complex with the C terminus of the pseudo kinase STE20-related adaptor. | Nat Struct Mol Biol | 2004 Feb |
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| 2 | 14985505 | The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. | Proc Natl Acad Sci U S A | 2004 Mar 9 |
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| 3 | 15261145 | The LKB1 tumor suppressor negatively regulates mTOR signaling. | Cancer Cell | 2004 Jul |
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| 4 | 15265871 | Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species. | J Biol Chem | 2004 Oct 15 |
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| 5 | 15561925 | AMP-activated protein kinase: a new beta-cell glucose sensor?: Regulation by amino acids and calcium ions. | Diabetes | 2004 Dec |
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| 6 | 15889149 | Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction. | EMBO J | 2005 May 18 |
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| 7 | 16308421 | The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. | Science | 2005 Dec 9 |
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| 8 | 16332922 | Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1. | Am J Physiol Endocrinol Metab | 2006 May |
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| 9 | 16407220 | Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells. | J Biol Chem | 2006 Mar 10 |
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| 10 | 16985256 | Effects of 3-phosphoglycerate and other metabolites on the activation of AMP-activated protein kinase by LKB1-STRAD-MO25. | Am J Physiol Endocrinol Metab | 2007 Feb |
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| 11 | 17023420 | Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP. | J Biol Chem | 2006 Dec 1 |
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| 12 | 17083919 | LKB1, an upstream AMPK kinase, regulates glucose and lipid metabolism in cultured liver and muscle cells. | Biochem Biophys Res Commun | 2006 Dec 22 |
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| 13 | 17255104 | Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase. | J Biol Chem | 2007 Mar 30 |
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| 14 | 17438283 | Resveratrol stimulates AMP kinase activity in neurons. | Proc Natl Acad Sci U S A | 2007 Apr 24 |
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| 15 | 17652778 | Opinion: alternative views of AMP-activated protein kinase. | Cell Biochem Biophys | 2007 |
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| 16 | 17786544 | AICAR induces phosphorylation of AMPK in an ATM-dependent, LKB1-independent manner. | Mol Cell Biochem | 2007 Dec |
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| 17 | 17875968 | Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner. | Circulation | 2007 Oct 2 |
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| 18 | 17925454 | LKB1 and the regulation of malonyl-CoA and fatty acid oxidation in muscle. | Am J Physiol Endocrinol Metab | 2007 Dec |
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| 19 | 18063805 | AMP-activated protein kinase phosphorylates transcription factors of the CREB family. | J Appl Physiol (1985) | 2008 Feb |
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| 20 | 18172296 | LKB1 deficiency sensitizes mice to carcinogen-induced tumorigenesis. | Cancer Res | 2008 Jan 1 |
5 |
| 21 | 18199555 | Phosphatidylinositol ether lipid analogues induce AMP-activated protein kinase-dependent death in LKB1-mutant non small cell lung cancer cells. | Cancer Res | 2008 Jan 15 |
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| 22 | 18387000 | Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice. | Biochem J | 2008 Jun 1 |
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| 23 | 18403917 | LKB1 and AMPK and the regulation of skeletal muscle metabolism. | Curr Opin Clin Nutr Metab Care | 2008 May |
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| 24 | 18435912 | Isodihydrocapsiate stimulates plasma glucose uptake by activation of AMP-activated protein kinase. | Biochem Biophys Res Commun | 2008 Jun 27 |
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| 25 | 18443001 | Premature aging in mice activates a systemic metabolic response involving autophagy induction. | Hum Mol Genet | 2008 Jul 15 |
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| 26 | 18474592 | Reactive nitrogen species is required for the activation of the AMP-activated protein kinase by statin in vivo. | J Biol Chem | 2008 Jul 18 |
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| 27 | 18796617 | Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle. | Diabetes | 2008 Dec |
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| 28 | 18812171 | AMPK activation by long chain fatty acyl analogs. | Biochem Pharmacol | 2008 Nov 15 |
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| 29 | 18854309 | Characterization of an alternative splice variant of LKB1. | J Biol Chem | 2009 Jan 2 |
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| 30 | 18854318 | C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest. | J Biol Chem | 2009 Jan 2 |
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| 31 | 19147279 | Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model. | Cancer Lett | 2009 May 18 |
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| 32 | 19159696 | Crucial role for LKB1 to AMPKalpha2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes. | Biochim Biophys Acta | 2009 Mar |
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| 33 | 19165340 | Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine. | PLoS One | 2009 |
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| 34 | 19177591 | Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation. | Hepatology | 2009 Feb |
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| 35 | 19332549 | Regulation of Rac1 by simvastatin in endothelial cells: differential roles of AMP-activated protein kinase and calmodulin-dependent kinase kinase-beta. | J Biol Chem | 2009 May 29 |
5 |
| 36 | 19336729 | Sunitinib prolongs survival in genetically engineered mouse models of multistep lung carcinogenesis. | Cancer Prev Res (Phila) | 2009 Apr |
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| 37 | 19434632 | Oral rapamycin reduces tumour burden and vascularization in Lkb1(+/-) mice. | J Pathol | 2009 Sep |
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| 38 | 19447226 | Catechin-induced activation of the LKB1/AMP-activated protein kinase pathway. | Biochem Pharmacol | 2009 Jul 1 |
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| 39 | 19541609 | mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome. | Proc Natl Acad Sci U S A | 2009 Jul 7 |
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| 40 | 19616619 | Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury. | Free Radic Biol Med | 2009 Oct 1 |
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| 41 | 19808021 | Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice. | Cell Metab | 2009 Oct |
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| 42 | 19828446 | Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. | J Biol Chem | 2009 Dec 18 |
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| 43 | 19874425 | Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner. | J Cell Mol Med | 2011 Jan |
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| 44 | 19932174 | Activation of the AMP-activated protein kinase-p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in p53-mutant mouse mammary tumor cells. | Cell Signal | 2010 Apr |
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| 45 | 19940131 | Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. | J Biol Chem | 2010 Jan 29 |
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| 46 | 20142099 | Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1. | Cell Metab | 2010 Feb 3 |
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| 47 | 20160076 | ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. | Proc Natl Acad Sci U S A | 2010 Mar 2 |
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| 48 | 20439172 | Arsenic inhibits neurite outgrowth by inhibiting the LKB1-AMPK signaling pathway. | Environ Health Perspect | 2010 May |
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| 49 | 20489196 | LKB1 deficiency in Tie2-Cre-expressing cells impairs ischemia-induced angiogenesis. | J Biol Chem | 2010 Jul 16 |
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| 50 | 20501876 | Nootkatone, a characteristic constituent of grapefruit, stimulates energy metabolism and prevents diet-induced obesity by activating AMPK. | Am J Physiol Endocrinol Metab | 2010 Aug |
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