serine/threonine kinase 11 ; Mus musculus






251 Article(s)
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51 20512929 Berberine suppresses neuroinflammatory responses through AMP-activated protein kinase activation in BV-2 microglia. J Cell Biochem 2010 Jun 1 1
52 20577053 Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J Clin Invest 2010 Jul 3
53 20585647 Involvement of AMPK in alcohol dehydrogenase accentuated myocardial dysfunction following acute ethanol challenge in mice. PLoS One 2010 Jun 23 1
54 20713714 Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle. Proc Natl Acad Sci U S A 2010 Aug 31 2
55 20873794 Antidiabetic and antiobesity effects of Ampkinone (6f), a novel small molecule activator of AMP-activated protein kinase. J Med Chem 2010 Oct 28 1
56 20956520 The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic-acid methyl ester has potent anti-diabetic effects in diet-induced diabetic mice and Lepr(db/db) mice. J Biol Chem 2010 Dec 24 2
57 21073663 Effect of LKB1 deficiency on mitochondrial content, fibre type and muscle performance in the mouse diaphragm. Acta Physiol (Oxf) 2011 Apr 1
58 21102522 Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo. Oncogene 2011 Mar 10 7
59 21118154 LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice. Biochem J 2011 Feb 15 4
60 21266325 Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice. Diabetes 2011 Mar 2
61 21312243 Regulation of AMP-activated protein kinase by LKB1 and CaMKK in adipocytes. J Cell Biochem 2011 May 2
62 21506122 Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell. J Cell Physiol 2011 Jul 2
63 21606593 Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling. J Clin Invest 2011 Jun 2
64 21689743 CNTF protects MIN6 cells against apoptosis induced by Alloxan and IL-1β through downregulation of the AMPK pathway. Cell Signal 2011 Oct 1
65 21903876 Characterization of the liver kinase B1-mouse protein-25 -Ste-20-related adaptor protein complex in adult mouse skeletal muscle. J Appl Physiol (1985) 2011 Dec 1
66 22183856 Retinoic acid receptor-related orphan receptor α-induced activation of adenosine monophosphate-activated protein kinase results in attenuation of hepatic steatosis. Hepatology 2012 May 4
67 22353783 Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis. Breast Cancer Res 2012 Feb 21 6
68 22363635 Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice. PLoS One 2012 1
69 22577519 Apo A1 Mimetic Rescues the Diabetic Phenotype of HO-2 Knockout Mice via an Increase in HO-1 Adiponectin and LKBI Signaling Pathway. Int J Hypertens 2012 1
70 22753194 Cyclin-dependent kinase 5-mediated hyperphosphorylation of sirtuin-1 contributes to the development of endothelial senescence and atherosclerosis. Circulation 2012 Aug 7 1
71 22916036 Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1. PLoS Genet 2012 1
72 22968146 Metformin affects the circadian clock and metabolic rhythms in a tissue-specific manner. Biochim Biophys Acta 2012 Nov 2
73 22983157 The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK. Nat Chem Biol 2012 Nov 2
74 23080146 Ion channel regulation by the LKB1-AMPK signalling pathway: the key to carotid body activation by hypoxia and metabolic homeostasis at the whole body level. Adv Exp Med Biol 2012 1
75 23349504 LKB1 regulates lipid oxidation during exercise independently of AMPK. Diabetes 2013 May 4
76 23352126 LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell 2013 Feb 11 2
77 23410967 The LKB1-AMPK pathway-friend or foe in cancer? Cancer Cell 2013 Feb 11 1
78 23451056 Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways. PLoS One 2013 1
79 23465594 Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis. J Nutr Biochem 2013 Aug 1
80 23515442 Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice. FASEB J 2013 Jul 2
81 23587332 AMP-activated protein kinase negatively regulates FcεRI-mediated mast cell signaling and anaphylaxis in mice. J Allergy Clin Immunol 2013 Sep 2
82 23637231 LKB1 represses focal adhesion kinase (FAK) signaling via a FAK-LKB1 complex to regulate FAK site maturation and directional persistence. J Biol Chem 2013 Jun 14 3
83 23695215 Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm. Am J Physiol Endocrinol Metab 2013 Jul 15 3
84 23704907 Small heterodimer partner-targeting therapy inhibits systemic inflammatory responses through mitochondrial uncoupling protein 2. PLoS One 2013 1
85 23715154 Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer. Cancer Discov 2013 Aug 1
86 23722652 N-methylnitrosourea aggravates gastrointestinal polyposis in Lkb1+/- mice. Carcinogenesis 2013 Oct 1
87 23765195 PAS kinase as a nutrient sensor in neuroblastoma and hypothalamic cells required for the normal expression and activity of other cellular nutrient and energy sensors. Mol Neurobiol 2013 Dec 1
88 23883619 Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes. Arthritis Res Ther 2013 Jul 25 1
89 23906616 Antineuroinflammatory effects of lycopene via activation of adenosine monophosphate-activated protein kinase-α1/heme oxygenase-1 pathways. Neurobiol Aging 2014 Jan 2
90 24086281 The LKB1 tumor suppressor as a biomarker in mouse and human tissues. PLoS One 2013 2
91 24093678 AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation. Cell Metab 2013 Oct 1 11
92 24376752 COH-SR4 reduces body weight, improves glycemic control and prevents hepatic steatosis in high fat diet-induced obese mice. PLoS One 2013 1
93 24560906 Thymoquinone alleviates thioacetamide-induced hepatic fibrosis and inflammation by activating LKB1-AMPK signaling pathway in mice. Int Immunopharmacol 2014 Apr 3
94 24586906 Disruption of Fyn SH3 domain interaction with a proline-rich motif in liver kinase B1 results in activation of AMP-activated protein kinase. PLoS One 2014 12
95 24643070 LKB1/AMPK and PKA control ABCB11 trafficking and polarization in hepatocytes. PLoS One 2014 1
96 24850909 Globular adiponectin inhibits ethanol-induced reactive oxygen species production through modulation of NADPH oxidase in macrophages: involvement of liver kinase B1/AMP-activated protein kinase pathway. Mol Pharmacol 2014 Sep 13
97 24877601 Convergence of IPMK and LKB1-AMPK signaling pathways on metformin action. Mol Endocrinol 2014 Jul 7
98 25069613 Lkb1 is indispensable for skeletal muscle development, regeneration, and satellite cell homeostasis. Stem Cells 2014 Nov 1
99 25070369 LKB1 and AMPK differentially regulate pancreatic β-cell identity. FASEB J 2014 Nov 1
100 25088745 The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver. Nat Commun 2014 Aug 4 1