Pub. Date : 2008 Jan 1
PMID : 18172296
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we uncover a marked sensitivity of Lkb1 mutant mice to the chemical carcinogen 7,12-dimethylbenz(a)anthracene (DMBA). | 7,12-dimethylbenz(a | serine/threonine kinase 11 | Mus musculus |
| 2 | Here, we uncover a marked sensitivity of Lkb1 mutant mice to the chemical carcinogen 7,12-dimethylbenz(a)anthracene (DMBA). | anthracene | serine/threonine kinase 11 | Mus musculus |
| 3 | Here, we uncover a marked sensitivity of Lkb1 mutant mice to the chemical carcinogen 7,12-dimethylbenz(a)anthracene (DMBA). | 9,10-Dimethyl-1,2-benzanthracene | serine/threonine kinase 11 | Mus musculus |
| 4 | Lkb1(+/-) mice are highly prone to DMBA-induced squamous cell carcinoma (SCC) of the skin and lung. | 9,10-Dimethyl-1,2-benzanthracene | serine/threonine kinase 11 | Mus musculus |
| 5 | Confirming a cell autonomous tumor suppressor role of Lkb1, mice with epidermal-specific Lkb1 deletion are also susceptible to DMBA-induced SCC and develop spontaneous SCC with long latency. | 9,10-Dimethyl-1,2-benzanthracene | serine/threonine kinase 11 | Mus musculus |