Title : Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction.

Pub. Date : 2009 Dec 18

PMID : 19828446






1 Functional Relationships(s)
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1 In cultured cardiac myocytes, LKB1 silencing induced hypertrophy, which was ameliorated by the expression of a constitutively active form AMPK or by treatment with the inhibitor of mTOR, rapamycin. Sirolimus serine/threonine kinase 11 Mus musculus