| 1 | 7581383 | Maternally inherited hearing loss, ataxia and myoclonus associated with a novel point mutation in mitochondrial tRNASer(UCN) gene. | Hum Mol Genet | 1995 Aug |
1 |
| 2 | 8019558 | A novel mitochondrial point mutation in a maternal pedigree with sensorineural deafness. | Hum Mutat | 1994 |
1 |
| 3 | 8500222 | Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C. | Cancer Chemother Pharmacol | 1993 |
4 |
| 4 | 8572257 | Mitochondrial mutation associated with nonsyndromic deafness. | Am J Otolaryngol | 1995 Nov-Dec |
1 |
| 5 | 8612563 | Cloning and characterization of human urocortin. | Endocrinology | 1996 May |
1 |
| 6 | 9098518 | Heterogeneity of signal transduction mechanisms in human basophils and human skin mast cells. II. Effects of 7-O-methyl-UCN-01, NPC 15437 and bryostatin 1 and 2, four protein kinase C-modulatory agents, on mediator release. | Biol Signals | 1997 Jan-Feb |
1 |
| 7 | 9108451 | G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells. | Cancer Res | 1997 Apr 15 |
1 |
| 8 | 9260909 | 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53. | Exp Cell Res | 1997 Aug 1 |
5 |
| 9 | 9606055 | Pharmacological characterisation of the recombinant human CRF binding protein using a simple assay. | J Neurosci Methods | 1998 Mar 13 |
2 |
| 10 | 9628819 | The structures of the mouse and human urocortin genes (Ucn and UCN). | Genomics | 1998 May 15 |
2 |
| 11 | 9832034 | A systematic mutation screen of 10 nuclear and 25 mitochondrial candidate genes in 21 patients with cytochrome c oxidase (COX) deficiency shows tRNA(Ser)(UCN) mutations in a subgroup with syndromal encephalopathy. | J Med Genet | 1998 Nov |
2 |
| 12 | 10222418 | Protein kinase C inhibition by UCN-01 induces apoptosis in human glioma cells in a time-dependent fashion. | J Neurooncol | 1999 Jan |
2 |
| 13 | 10485490 | Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling drug UCN-01 (7-Hydroxystaurosporine). | Cancer Res | 1999 Sep 1 |
2 |
| 14 | 10499638 | RB status as a determinant of response to UCN-01 in non-small cell lung carcinoma. | Clin Cancer Res | 1999 Sep |
4 |
| 15 | 10545608 | Molecular phenotype of the np 7472 deafness-associated mitochondrial mutation in osteosarcoma cell cybrids. | Hum Mol Genet | 1999 Nov |
3 |
| 16 | 10577941 | Heterogenous point mutations in the mitochondrial tRNA Ser(UCN) precursor coexisting with the A1555G mutation in deaf students from Mongolia. | Am J Hum Genet | 1999 Dec |
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| 17 | 10614646 | Urocortin expression in the Edinger-Westphal nucleus is up-regulated by stress and corticotropin-releasing hormone deficiency. | Endocrinology | 2000 Jan |
1 |
| 18 | 10629089 | Molecular determinants of UCN-01-induced growth inhibition in human lung cancer cells. | Int J Cancer | 2000 Jan 15 |
1 |
| 19 | 10648719 | Do centrally administered neuropeptides access cognate receptors?: an analysis in the central corticotropin-releasing factor system. | J Neurosci | 2000 Feb 1 |
1 |
| 20 | 10648728 | Chronic administration of the triazolobenzodiazepine alprazolam produces opposite effects on corticotropin-releasing factor and urocortin neuronal systems. | J Neurosci | 2000 Feb 1 |
1 |
| 21 | 10665655 | G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation. | Jpn J Cancer Res | 1999 Dec |
2 |
| 22 | 10681541 | The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. | J Biol Chem | 2000 Feb 25 |
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| 23 | 10764807 | Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase. | J Biol Chem | 2000 Jun 30 |
2 |
| 24 | 10857990 | UCN-01 enhances the in vitro toxicity of clinical agents in human tumor cell lines. | Invest New Drugs | 2000 May |
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| 25 | 10887097 | Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia. | Blood | 2000 Jul 15 |
2 |
| 26 | 11020446 | Potentiation of 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial damage and apoptosis in human leukemia cells (U937) overexpressing bcl-2 by the kinase inhibitor 7-hydroxystaurosporine (UCN-01). | Biochem Pharmacol | 2000 Nov 15 |
7 |
| 27 | 11033056 | The neurobiology of urocortin. | Regul Pept | 2000 Sep 25 |
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| 28 | 11087261 | Urocortin, a member of the corticotropin-releasing factor family, in normal and diseased heart. | Am J Physiol Heart Circ Physiol | 2000 Dec |
2 |
| 29 | 11095927 | Localization and characterization of urocortin during human pregnancy. | Placenta | 2000 Nov |
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| 30 | 11117536 | Urocortin, but not corticotropin-releasing hormone (CRH), activates the mitogen-activated protein kinase signal transduction pathway in human pregnant myometrium: an effect mediated via R1alpha and R2beta CRH receptor subtypes and stimulation of Gq-proteins. | Mol Endocrinol | 2000 Dec |
3 |
| 31 | 11525264 | Susceptibility of thyroid cancer cells to 7-hydroxystaurosporine-induced apoptosis correlates with Bcl-2 protein level. | Thyroid | 2001 Aug |
2 |
| 32 | 11577083 | Dual mode recognition of two isoacceptor tRNAs by mammalian mitochondrial seryl-tRNA synthetase. | J Biol Chem | 2001 Dec 14 |
2 |
| 33 | 11788672 | Expression of urocortin and corticotropin-releasing factor receptor subtypes in the human heart. | J Clin Endocrinol Metab | 2002 Jan |
1 |
| 34 | 11836692 | [Screening for mitochondrial DNA mutation in two pedigrees with nonsyndromic inherited sensorineural hearing loss]. | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | 2002 Feb |
1 |
| 35 | 11864911 | Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive. | Cell Growth Differ | 2002 Feb |
1 |
| 36 | 11919191 | The 7472insC mitochondrial DNA mutation impairs the synthesis and extent of aminoacylation of tRNASer(UCN) but not its structure or rate of turnover. | J Biol Chem | 2002 Jun 21 |
5 |
| 37 | 11984070 | Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells. | Anticancer Drugs | 2002 Mar |
3 |
| 38 | 12007627 | Urocortin. | Int J Biochem Cell Biol | 2002 Aug |
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| 39 | 12175707 | Urocortin has cell-proliferative effects on cardiac non-myocytes. | Life Sci | 2002 Sep 6 |
7 |
| 40 | 12177808 | Abrogation of the radiation-induced G2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines. | Br J Cancer | 2002 Jul 29 |
1 |
| 41 | 12384533 | UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1. | Cancer Res | 2002 Oct 15 |
2 |
| 42 | 12429646 | Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1). | Clin Cancer Res | 2002 Nov |
1 |
| 43 | 12429947 | UCN-01 (7-hydroxystauorsporine) blocks PMA-induced maturation and reciprocally promotes apoptosis in human myelomonocytic leukemia cells (U937). | Cell Cycle | 2002 Jul-Aug |
3 |
| 44 | 12513198 | Measurements of ultracold-neutron lifetimes in solid deuterium. | Phys Rev Lett | 2002 Dec 30 |
1 |
| 45 | 12535698 | Novel peptide-peptide cooperation may transform feeding behavior. | Peptides | 2002 Dec |
1 |
| 46 | 12615968 | Intracellular calcium measurements of single human skin cells after stimulation with corticotropin-releasing factor and urocortin using confocal laser scanning microscopy. | J Cell Sci | 2003 Apr 1 |
1 |
| 47 | 12642693 | Coadministration of UCN-01 with MEK1/2 inhibitors potently induces apoptosis in BCR/ABL+ leukemia cells sensitive and resistant to ST1571. | Cancer Biol Ther | 2002 Nov-Dec |
2 |
| 48 | 12721762 | Cell cycle-dependent potentiation of cisplatin by UCN-01 in non-small-cell lung carcinoma. | Cancer Chemother Pharmacol | 2003 Apr |
4 |
| 49 | 12746287 | High levels of intrauterine corticotropin-releasing hormone, urocortin, tryptase, and interleukin-8 in spontaneous abortions. | Endocrinology | 2003 Jun |
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| 50 | 12903362 | Translation activity of mitochondrial tRNA with unusual secondary structure. | Nucleic Acids Symp Ser | 2000 |
2 |