Title : Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling drug UCN-01 (7-Hydroxystaurosporine).

Pub. Date : 1999 Sep 1

PMID : 10485490






2 Functional Relationships(s)
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1 Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling drug UCN-01 (7-Hydroxystaurosporine). 7-hydroxystaurosporine urocortin Homo sapiens
2 7-Hydroxystaurosporine (UCN-01) is a protein kinase inhibitor that is under development as an anticancer agent in the United States and Japan. 7-hydroxystaurosporine urocortin Homo sapiens