| Protein Name | urocortin |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 7349 |
| Gene Symbol | UCN |
| UniProt | P55089 (UCN1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
144
Total Number of Articles : 159 |
Description |
urocortin |
| Gene Summary |
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family. The encoded preproprotein is proteolytically processed to generate the mature peptide, an endogenous ligand for both corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. In the brain this peptide may be responsible for the effects of stress on appetite. This peptide may also play a role in mood disorders, neurodegeneration, and skeletal system disorders. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin-2. [provided by RefSeq, Feb 2016] |
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| Properties | |