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6 |
| 2 | 10818227 | The RIP-like kinase, RIP3, induces apoptosis and NF-kappaB nuclear translocation and localizes to mitochondria. | FEBS Lett | 2000 May 19 |
2 |
| 3 | 16429275 | Homocysteine, hRIP3 and congenital cardiovascular malformations. | Anat Embryol (Berl) | 2006 Jun |
1 |
| 4 | 17644308 | Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. | Cell Signal | 2007 Oct |
1 |
| 5 | 18025550 | Cloning, overexpression, purification, and characterization of receptor-interacting protein 3 truncation in Escherichia coli. | Appl Biochem Biotechnol | 2007 May-Jun |
2 |
| 6 | 19524513 | Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. | Cell | 2009 Jun 12 |
1 |
| 7 | 19690434 | Expression of two inflammation-related genes (RIPK3 and RNF216) in mononuclear cells is associated with weight-loss regain in obese subjects. | J Nutrigenet Nutrigenomics | 2009 |
1 |
| 8 | 21052097 | cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production. | Cell Death Differ | 2011 Apr |
3 |
| 9 | 21962882 | Necroptosis: an emerging form of programmed cell death. | Crit Rev Oncol Hematol | 2012 Jun |
1 |
| 10 | 22033613 | 5-ALA-PDT induces RIP3-dependent necrosis in glioblastoma. | Photochem Photobiol Sci | 2011 Dec |
2 |
| 11 | 22057483 | RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT. | Lasers Surg Med | 2011 Sep |
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| 12 | 22265413 | Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. | Cell | 2012 Jan 20 |
6 |
| 13 | 22357656 | Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development. | Hum Mol Genet | 2012 May 15 |
2 |
| 14 | 22817896 | The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. | Cell | 2012 Jul 20 |
3 |
| 15 | 23144495 | Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner. | J Immunol | 2012 Dec 15 |
1 |
| 16 | 23162759 | TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis. | Oncoimmunology | 2012 Sep 1 |
1 |
| 17 | 23261677 | Shikonin induces programmed necrosis-like cell death through the formation of receptor interacting protein 1 and 3 complex. | Food Chem Toxicol | 2013 May |
1 |
| 18 | 23525116 | Cyclophilin D modulates cell death transition from early apoptosis to programmed necrosis induced by honokiol. | Int J Oncol | 2013 May |
2 |
| 19 | 23612963 | Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling. | J Biol Chem | 2013 Jun 7 |
4 |
| 20 | 23831571 | A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy. | Oncogene | 2014 Jun 5 |
5 |
| 21 | 23892367 | RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition. | Cell Death Differ | 2013 Oct |
1 |
| 22 | 24048737 | MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma. | Mol Cancer Ther | 2013 Nov |
1 |
| 23 | 24103001 | RIPK3-mediated necroptosis promotes donor kidney inflammatory injury and reduces allograft survival. | Am J Transplant | 2013 Nov |
1 |
| 24 | 24268776 | Widespread mitochondrial depletion via mitophagy does not compromise necroptosis. | Cell Rep | 2013 Nov 27 |
2 |
| 25 | 24314238 | The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis. | BMC Cancer | 2013 Dec 6 |
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| 26 | 24889371 | Consequences of activating the calcium-permeable ion channel TRPV1 in breast cancer cells with regulated TRPV1 expression. | Cell Calcium | 2014 Aug |
1 |
| 27 | 24901049 | The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury. | Cell Death Dis | 2014 Jun 5 |
13 |
| 28 | 24902899 | RIPK1- and RIPK3-induced cell death mode is determined by target availability. | Cell Death Differ | 2014 Oct |
1 |
| 29 | 24909514 | RIP3 overexpression sensitizes human breast cancer cells to parthenolide in vitro via intracellular ROS accumulation. | Acta Pharmacol Sin | 2014 Jul |
10 |
| 30 | 24959694 | Receptor interactive protein kinase 3 promotes Cisplatin-triggered necrosis in apoptosis-resistant esophageal squamous cell carcinoma cells. | PLoS One | 2014 |
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| 31 | 24984764 | RIPK3-mediated necroptosis regulates cardiac allograft rejection. | Am J Transplant | 2014 Aug |
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| 32 | 24993301 | The role of RIP3 mediated necroptosis in ouabain-induced spiral ganglion neurons injuries. | Neurosci Lett | 2014 Aug 22 |
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| 33 | 25180169 | Innate immunity and cell death in alcoholic liver disease: role of cytochrome P4502E1. | Redox Biol | 2014 |
3 |
| 34 | 25349782 | Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure. | FEBS Open Bio | 2014 |
2 |
| 35 | 25412314 | Combination simvastatin and metformin induces G1-phase cell cycle arrest and Ripk1- and Ripk3-dependent necrosis in C4-2B osseous metastatic castration-resistant prostate cancer cells. | Cell Death Dis | 2014 Nov 20 |
2 |
| 36 | 25593994 | Necroptosis is associated with low procaspase-8 and active RIPK1 and -3 in human glioma cells. | Oncoscience | 2014 |
5 |
| 37 | 25697054 | 24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8. | Steroids | 2015 Jul |
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| 38 | 25698398 | Necroptosis-inducing rhenium(V) oxo complexes. | J Am Chem Soc | 2015 Mar 4 |
3 |
| 39 | 25748555 | Upregulated RIP3 Expression Potentiates MLKL Phosphorylation-Mediated Programmed Necrosis in Toxic Epidermal Necrolysis. | J Invest Dermatol | 2015 Aug |
2 |
| 40 | 25801024 | Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1. | Cell Rep | 2015 Mar 24 |
1 |
| 41 | 25824798 | Cobalt chloride induces necroptosis in human colon cancer HT-29 cells. | Asian Pac J Cancer Prev | 2015 |
2 |
| 42 | 25852146 | A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis. | Proc Natl Acad Sci U S A | 2015 Apr 21 |
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| 43 | 25858093 | The serine threonine kinase RIP3: lost and found. | BMB Rep | 2015 Jun |
1 |
| 44 | 25867066 | Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death. | Oncogene | 2015 Nov 19 |
3 |
| 45 | 25926385 | Analysis of the downstream mediators of toll-like receptor 3-induced apoptosis in labial salivary glands in patients with Sjögren's syndrome. | Mod Rheumatol | 2016 |
6 |
| 46 | 25939025 | The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis. | Nat Immunol | 2015 Jun |
2 |
| 47 | 25939952 | FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. | Toxicol Lett | 2015 Jul 2 |
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| 48 | 25996294 | A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis. | Cell Death Dis | 2015 May 21 |
2 |
| 49 | 25997957 | Receptor-interacting protein kinase 3 is a predictor of survival and plays a tumor suppressive role in colorectal cancer. | Neoplasma | 2015 |
1 |
| 50 | 26174536 | RIPping the Skin Apart: Necroptosis Signaling in Toxic Epidermal Necrolysis. | J Invest Dermatol | 2015 Aug |
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