Title : The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.

Pub. Date : 2013 Dec 6

PMID : 24314238






1 Functional Relationships(s)
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1 After 8-hour treatment of shikonin, the expression levels of RIP1 and RIP3 were increased while caspase-3, caspase-6 and PARP were not activated in K7 and U2OS cells determined by Western blot. shikonin receptor interacting serine/threonine kinase 3 Homo sapiens