Title : Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling.

Pub. Date : 2013 Jun 7

PMID : 23612963






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Phosphorylation on Ser-227 in human RIP3 (hRIP3) is required for its interaction with human mixed lineage kinase domain-like (MLKL) in the necrosome, a signaling complex induced by TNF stimulation. Serine receptor interacting serine/threonine kinase 3 Homo sapiens
2 Phosphorylation on Ser-227 in human RIP3 (hRIP3) is required for its interaction with human mixed lineage kinase domain-like (MLKL) in the necrosome, a signaling complex induced by TNF stimulation. Serine receptor interacting serine/threonine kinase 3 Homo sapiens
3 Ser-232 in mRIP3 corresponds to Ser-227 in hRIP3, whereas Thr-231 is not conserved in hRIP3. Serine receptor interacting serine/threonine kinase 3 Homo sapiens
4 Ser-232 in mRIP3 corresponds to Ser-227 in hRIP3, whereas Thr-231 is not conserved in hRIP3. Serine receptor interacting serine/threonine kinase 3 Homo sapiens