regulator of calcineurin 1 ; Homo sapiens






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1 8595418 A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart. Hum Mol Genet 1995 Oct 3
2 9593683 Interaction of cysteine string proteins with the alpha1A subunit of the P/Q-type calcium channel. J Biol Chem 1998 May 29 1
3 10415113 adapt78, a stress-inducible mRNA, is related to the glucose-regulated protein family of genes. Arch Biochem Biophys 1999 Aug 1 11
4 10423286 Efficient access to all four stereoisomers of phenylalanine cyclopropane analogues by chiral HPLC Chirality 1999 1
5 10435350 Preparation and evaluation of new Pirkle type chiral stationary phases with long alkyl chains for the separation of amino acid enantiomers derivatized with NBD-F. Analyst 1998 Dec 2
6 10898938 adapt78 protects cells against stress damage and suppresses cell growth. Arch Biochem Biophys 2000 Jul 15 2
7 11174179 Novel chiral stationary phases comprising 2,4-(or 2,6)-diamino-5,6-(or 2,5)-dichlorobenzene-1,3-dicarbonitrile and 1-acyl (1R,2R)-diaminocyclohexane. Enantiomer 2000 1
8 11438962 A study of chiral recognition for NBD-derivatives on a Pirkle-type chiral stationary phase. Biomed Chromatogr 2001 Jun 10
9 11483593 Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease. J Biol Chem 2001 Oct 19 2
10 11667409 Intermolecular (1)H-(1)H Two-Dimensional Nuclear Overhauser Enhancements in the Characterization of a Rationally Designed Chiral Recognition System. J Org Chem 1996 Jul 12 1
11 11968074 NMR studies of chiral discrimination relevant to the enantioseparation of N-acylarylalkylamines by an (R)-phenylglycinol-derived chiral selector. Chirality 2002 May 5 4
12 12016333 The essential role of calcium in induction of the DSCR1 (ADAPT78) gene. Biofactors 2001 2
13 12039863 The DSCR1 (Adapt78) isoform 1 protein calcipressin 1 inhibits calcineurin and protects against acute calcium-mediated stress damage, including transient oxidative stress. FASEB J 2002 Jun 11
14 12112346 Liquid chromatographic resolution of N-acyl-alpha-amino acids as their anilide derivatives on a chiral stationary phase based on (S)-leucine. Chirality 2002 Jun 9
15 12680769 Structural and functional analysis of caspase active sites. Biochemistry 2003 Apr 15 1
16 12774294 Enantioseparation of racemic 4-aryl-3,4-dihydro-2(1H)-pyrimidones on chiral stationary phases based on 3,5-dimethylanilides of N-(4-alkylamino-3,5-dinitro)benzoyl L-alpha-amino acids. Chirality 2003 Jun 1
17 12927602 Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein. Free Radic Biol Med 2003 Sep 1 20
18 14718387 DSCR1(Adapt78) modulates expression of SOD1. FASEB J 2004 Jan 2
19 14976250 A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway. Proc Natl Acad Sci U S A 2004 Mar 2 4
20 15256217 Multiple oxidative stress-response members of the Adapt78 family. Free Radic Biol Med 2004 Aug 15 4
21 15263820 Down syndrome candidate region 1,a downstream target of VEGF, participates in endothelial cell migration and angiogenesis. J Vasc Res 2004 Jul-Aug 4
22 15358155 VEGF selectively induces Down syndrome critical region 1 gene expression in endothelial cells: a mechanism for feedback regulation of angiogenesis? Biochem Biophys Res Commun 2004 Aug 27 1
23 15610015 The variable C-terminus of cysteine string proteins modulates exocytosis and protein-protein interactions. Biochemistry 2004 Dec 28 1
24 15729817 New hybrid polymeric liquid chromatography chiral stationary phase prepared by surface-initiated polymerization. J Chromatogr A 2005 Jan 28 7
25 15975916 Depolarization of neural cells induces transcription of the Down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated T cells-dependent pathway. J Biol Chem 2005 Aug 19 4
26 16109302 Redox response of the endogenous calcineurin inhibitor Adapt 78. Free Radic Biol Med 2005 Sep 15 3
27 16123779 Caspase-1 activation of caspase-6 in human apoptotic neurons. Cell Death Differ 2006 Feb 1
28 16627481 Thrombin-induced autoinhibitory factor, Down syndrome critical region-1, attenuates NFAT-dependent vascular cell adhesion molecule-1 expression and inflammation in the endothelium. J Biol Chem 2006 Jul 21 1
29 16716332 The role of molecular interaction fields on enantioselective and nonselective separation of chiral sulfoxides. J Chromatogr A 2006 Jul 14 1
30 16894785 Extended application of a chiral stationary phase based on (+)-(1 8-crown-6)-2,3,11,12-tetracarboxylic acid to the resolution of N-(substituted benzoyl)-alpha-amino acid amides. J Sep Sci 2006 Jul 11
31 17062574 Down syndrome candidate region 1 increases the stability of the IkappaBalpha protein: implications for its anti-inflammatory effects. J Biol Chem 2006 Dec 22 2
32 17114339 Down syndrome candidate region 1 isoform 1 mediates angiogenesis through the calcineurin-NFAT pathway. Mol Cancer Res 2006 Nov 2
33 17264507 Mechanisms of Ca2+-dependent calcineurin activation in mechanical stretch-induced hypertrophy. Cardiology 2007 1
34 17341486 RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration. Hum Mol Genet 2007 May 1 2
35 18293408 Calcium/calcineurin signaling in primary cortical astrocyte cultures: Rcan1-4 and cyclooxygenase-2 as NFAT target genes. Glia 2008 May 6
36 18325738 System-level investigation into the regulatory mechanism of the calcineurin/NFAT signaling pathway. Cell Signal 2008 Jun 1
37 18575781 Oxidative stress-induced ubiquitination of RCAN1 mediated by SCFbeta-TrCP ubiquitin ligase. Int J Mol Med 2008 Jul 13
38 19036088 Regulation of Down Syndrome Critical Region 1 expression by Nuclear Factor of Activated T cells in megakaryocytes. Br J Haematol 2009 Feb 2
39 19189965 Inhibiting the calcineurin-NFAT (nuclear factor of activated T cells) signaling pathway with a regulator of calcineurin-derived peptide without affecting general calcineurin phosphatase activity. J Biol Chem 2009 Apr 3 2
40 19270310 Regulator of calcineurin (RCAN1-1L) is deficient in Huntington disease and protective against mutant huntingtin toxicity in vitro. J Biol Chem 2009 May 1 1
41 19319988 Synthesis of dendrimer-type chiral stationary phases based on the selector of (1S,2R)-(+)-2-amino-1,2-diphenylethanol derivate and their enantioseparation evaluation by HPLC. Chirality 2010 Jan 1
42 19322033 Down syndrome critical region 1 enhances the proteolytic cleavage of calcineurin. Exp Mol Med 2009 Jul 31 2
43 19725972 Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. J Mol Signal 2009 Sep 2 10
44 19755121 Activation of adenylate cyclase by forskolin increases the protein stability of RCAN1 (DSCR1 or Adapt78). FEBS Lett 2009 Oct 6 10
45 19891949 A fluorescent polarization-based assay for the identification of disruptors of the RCAN1-calcineurin A protein complex. Anal Biochem 2010 Mar 1 1
46 19914243 Differential functions of genes regulated by VEGF-NFATc1 signaling pathway in the migration of pulmonary valve endothelial cells. FEBS Lett 2010 Jan 4 1
47 20054496 Knockdown of RCAN1.4 Increases Susceptibility to FAS-mediated and DNA-damage-induced Apoptosis by Upregulation of p53 Expression. Korean J Physiol Pharmacol 2009 Dec 3
48 20351753 A low-risk ZnT-8 allele (W325) for post-transplantation diabetes mellitus is protective against cyclosporin A-induced impairment of insulin secretion. Pharmacogenomics J 2011 Jun 1
49 20806236 Temperature effects on a doubly tethered diproline chiral stationary phase: Hold-up volume, enantioselectivity and robustness. J Sep Sci 2010 Oct 4
50 20828702 Liquid chromatographic resolution of proton pump inhibitors including omeprazole on a ligand exchange chiral stationary phase. J Chromatogr A 2010 Oct 8 5