Pub. Date : 1999 Aug 1
PMID : 10415113
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have recently reported a new oxidant- and calcium-inducible mRNA, adapt78, from hamster HA-1 cells. | Calcium | regulator of calcineurin 1 | Homo sapiens |
| 2 | In HA-1 cells, adapt78 mRNA was induced by the calcium ionophore A23187, 2-deoxyglucose, brefeldin A, tunicamycin, thapsigargin, and cyclopiazonic acid, with thapsigargin being the most potent inducer (7.3-fold). | Calcium | regulator of calcineurin 1 | Homo sapiens |
| 3 | In HA-1 cells, adapt78 mRNA was induced by the calcium ionophore A23187, 2-deoxyglucose, brefeldin A, tunicamycin, thapsigargin, and cyclopiazonic acid, with thapsigargin being the most potent inducer (7.3-fold). | Calcimycin | regulator of calcineurin 1 | Homo sapiens |
| 4 | In HA-1 cells, adapt78 mRNA was induced by the calcium ionophore A23187, 2-deoxyglucose, brefeldin A, tunicamycin, thapsigargin, and cyclopiazonic acid, with thapsigargin being the most potent inducer (7.3-fold). | Deoxyglucose | regulator of calcineurin 1 | Homo sapiens |
| 5 | In HA-1 cells, adapt78 mRNA was induced by the calcium ionophore A23187, 2-deoxyglucose, brefeldin A, tunicamycin, thapsigargin, and cyclopiazonic acid, with thapsigargin being the most potent inducer (7.3-fold). | Brefeldin A | regulator of calcineurin 1 | Homo sapiens |
| 6 | In HA-1 cells, adapt78 mRNA was induced by the calcium ionophore A23187, 2-deoxyglucose, brefeldin A, tunicamycin, thapsigargin, and cyclopiazonic acid, with thapsigargin being the most potent inducer (7.3-fold). | Tunicamycin | regulator of calcineurin 1 | Homo sapiens |
| 7 | In HA-1 cells, adapt78 mRNA was induced by the calcium ionophore A23187, 2-deoxyglucose, brefeldin A, tunicamycin, thapsigargin, and cyclopiazonic acid, with thapsigargin being the most potent inducer (7.3-fold). | Thapsigargin | regulator of calcineurin 1 | Homo sapiens |
| 8 | In HA-1 cells, adapt78 mRNA was induced by the calcium ionophore A23187, 2-deoxyglucose, brefeldin A, tunicamycin, thapsigargin, and cyclopiazonic acid, with thapsigargin being the most potent inducer (7.3-fold). | cyclopiazonic acid | regulator of calcineurin 1 | Homo sapiens |
| 9 | In HA-1 cells, adapt78 mRNA was induced by the calcium ionophore A23187, 2-deoxyglucose, brefeldin A, tunicamycin, thapsigargin, and cyclopiazonic acid, with thapsigargin being the most potent inducer (7.3-fold). | Thapsigargin | regulator of calcineurin 1 | Homo sapiens |
| 10 | Differences were also observed, as adapt78 mRNA but not grp78 mRNA was induced by 160 microM hydrogen peroxide, and adapt78 demonstrated earlier induction kinetics for certain agents compared with grp78. | Hydrogen Peroxide | regulator of calcineurin 1 | Homo sapiens |
| 11 | A23187 had the strongest effect on adapt78 mRNA levels in human cells, inducing greater than 20-fold in all human cell cultures tested. | Calcimycin | regulator of calcineurin 1 | Homo sapiens |