sirtuin 7 ; Homo sapiens






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1 19174463 Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis. J Cell Sci 2009 Feb 15 1
2 22698398 A big step for SIRT7, one giant leap for Sirtuins… in cancer. Cancer Cell 2012 Jun 12 1
3 22722849 SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature 2012 Jul 5 2
4 23079745 Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b. Hepatology 2013 Mar 2
5 23680022 Intracellular distribution of human SIRT7 and mapping of the nuclear/nucleolar localization signal. FEBS J 2013 Jul 3
6 23750001 Sirtuin-7 inhibits the activity of hypoxia-inducible factors. J Biol Chem 2013 Jul 19 1
7 24113281 Sirtuin 7 plays a role in ribosome biogenesis and protein synthesis. Mol Cell Proteomics 2014 Jan 1
8 24134843 Inhibition of H3K18 deacetylation of Sirt7 by Myb-binding protein 1a (Mybbp1a). Biochem Biophys Res Commun 2013 Nov 8 1
9 24536059 Molecular pathways: emerging roles of mammalian Sirtuin SIRT7 in cancer. Clin Cancer Res 2014 Apr 1 2
10 25200183 A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function. Cell Metab 2014 Nov 4 1
11 25445786 Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response. Exp Cell Res 2015 Feb 1 5
12 25644192 Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells. Toxicol Lett 2015 Mar 18 2
13 25860861 Sirt7 promotes gastric cancer growth and inhibits apoptosis by epigenetically inhibiting miR-34a. Sci Rep 2015 Apr 10 1
14 25921180 SIRT7 Exhibits Oncogenic Potential in Human Ovarian Cancer Cells. Asian Pac J Cancer Prev 2015 2
15 25970806 Stressed SIRT7: facing a crossroad of senescence and immortality. Clin Exp Pharmacol Physiol 2015 Jun 1
16 26112889 Protective effects of sirtuins in cardiovascular diseases: from bench to bedside. Eur Heart J 2015 Dec 21 2
17 26704017 C/EBPα negatively regulates SIRT7 expression via recruiting HDAC3 to the upstream-promoter of hepatocellular carcinoma cells. Biochim Biophys Acta 2016 Feb 1
18 26704979 Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. Nucleic Acids Res 2016 May 5 4
19 26770454 miR-125b suppresses the proliferation of hepatocellular carcinoma cells by targeting Sirtuin7. Int J Clin Exp Med 2015 4
20 26907567 SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context. ACS Chem Biol 2016 Mar 18 1
21 27246221 Molecular, Cellular, and Physiological Characterization of Sirtuin 7 (SIRT7). Methods Mol Biol 2016 2
22 27498548 SIRT7, H3K18ac, and ELK4 Immunohistochemical Expression in Hepatocellular Carcinoma. J Pathol Transl Med 2016 Sep 1
23 27882448 Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders. Neurochem Res 2017 Mar 1
24 27997115 SIRT7 Is an RNA-Activated Protein Lysine Deacylase. ACS Chem Biol 2017 Jan 20 8
25 28426094 SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. Nucleic Acids Res 2017 Mar 17 3
26 28435470 Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer. Theranostics 2017 6
27 28655758 Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis. J Biol Chem 2017 Aug 11 6
28 28675767 Sirtuin7 is involved in protecting neurons against oxygen-glucose deprivation and reoxygenation-induced injury through regulation of the p53 signaling pathway. J Biochem Mol Toxicol 2017 Oct 2
29 28772218 Suppression of microRNA-142-5p attenuates hypoxia-induced apoptosis through targeting SIRT7. Biomed Pharmacother 2017 Oct 2
30 28827661 SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis. Nat Commun 2017 Aug 22 1
31 28849008 microRNA-20b contributes to high glucose-induced podocyte apoptosis by targeting SIRT7. Mol Med Rep 2017 Oct 1
32 28886238 SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes. FEBS J 2017 Nov 2
33 29100388 Sirtuin 7: a new marker of aggressiveness in prostate cancer. Oncotarget 2017 Sep 29 1
34 29231244 SIRT7 depletion inhibits cell proliferation, migration, and increases drug sensitivity by activating p38MAPK in breast cancer cells. J Cell Physiol 2018 Sep 4
35 29305011 Transcriptional Regulation of Metabolism by SIRT1 and SIRT7. Int Rev Cell Mol Biol 2018 1
36 29710664 MicroRNA-340 inhibits the growth and invasion of angiosarcoma cells by targeting SIRT7. Biomed Pharmacother 2018 Jul 3
37 29879377 SIRT7 functions in redox homeostasis and cytoskeletal organization during oocyte maturation. FASEB J 2018 Jun 7 1
38 29888767 Chromatin Succinylation Correlates with Active Gene Expression and Is Perturbed by Defective TCA Cycle Metabolism. iScience 2018 Apr 27 1
39 30090057 The Role of SIRT3 in the Brain Under Physiological and Pathological Conditions. Front Cell Neurosci 2018 2
40 30093732 Diabetes induces fibrotic changes in the lung through the activation of TGF-β signaling pathways. Sci Rep 2018 Aug 9 1
41 30282801 Sirtuin 7-mediated deacetylation of WD repeat domain 77 (WDR77) suppresses cancer cell growth by reducing WDR77/PRMT5 transmethylase complex activity. J Biol Chem 2018 Nov 16 6
42 30348528 Depletion of SIRT7 sensitizes human non-small cell lung cancer cells to gemcitabine therapy by inhibiting autophagy. Biochem Biophys Res Commun 2018 Nov 17 4
43 30453040 The roles of sirtuins family in cell metabolism during tumor development. Semin Cancer Biol 2019 Aug 1
44 30540930 SIRT7-Dependent Deacetylation of Fibrillarin Controls Histone H2A Methylation and rRNA Synthesis during the Cell Cycle. Cell Rep 2018 Dec 11 1
45 30559718 Distinctive Roles of Sirtuins on Diabetes, Protective or Detrimental? Front Endocrinol (Lausanne) 2018 1
46 30578034 Cyclic tripeptide-based potent human SIRT7 inhibitors. Bioorg Med Chem Lett 2019 Feb 1 2
47 30655851 Sirtuin-7 knockdown inhibits the growth of endometrial cancer cells by inducing apoptosis via the NF-κB signaling pathway. Oncol Lett 2019 Jan 2
48 30756531 [Progress in roles and mechanisms of deacetylase SIRT7]. Sheng Wu Gong Cheng Xue Bao 2019 Jan 25 1
49 31025603 Role of <i>N</i>-terminus in function and dynamics of sirtuin 7: an <i>in silico</i> study. J Biomol Struct Dyn 2020 Mar 3
50 31075303 SIRT7 regulates the nuclear export of NF-κB p65 by deacetylating Ran. Biochim Biophys Acta Mol Cell Res 2019 Sep 2