Protein Name sirtuin 7
Organism Homo sapiens
Gene ID 51547
Gene Symbol

SIRT7

UniProt Q9NRC8 (SIR7_HUMAN)
Relationships Total Number of functionally related compound(s) : 77
Total Number of Articles : 87
Description

sirtuin 7

Gene Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]

synonyms
  • NAD-dependent protein deacetylase sirtuin-7
  • NAD-dependent deacetylase sirtuin-7
  • NAD-dependent protein deacylase sirtuin-7
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Properties