CPRiL

SIRT7

sirtuin 7

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]

• NAD-dependent protein deacetylase sirtuin-7
• NAD-dependent deacetylase sirtuin-7
• NAD-dependent protein deacylase sirtuin-7
SIR2-like protein 7
regulatory protein SIR2 homolog 7
silent mating type information regulation 2, S.cerevisiae, homolog 7
sir2-related protein type 7
sirtuin type 7
SIR2L7