Pub. Date : 2018 Nov 17
PMID : 30348528
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Depletion of SIRT7 sensitizes human non-small cell lung cancer cells to gemcitabine therapy by inhibiting autophagy. | gemcitabine | sirtuin 7 | Homo sapiens |
| 2 | In our study, we find that SIRT7 protein level elevated dramatically in response to an anti-metabolic drug-gemcitabine treatment. | gemcitabine | sirtuin 7 | Homo sapiens |
| 3 | Moreover, autophagy induced by gemcitabine in non-small cell lung cancer cells is SIRT7-dependent. | gemcitabine | sirtuin 7 | Homo sapiens |
| 4 | Furthermore, depletion of SIRT7 promoted Gemcitabine-induced cell death. | gemcitabine | sirtuin 7 | Homo sapiens |