Pub. Date : 2018 Sep
PMID : 29231244
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Meanwhile, SIRT7 depletion can increase the sensitivity of breast cancer cells to doxorubicin (DOX). | Doxorubicin | sirtuin 7 | Homo sapiens |
| 2 | Meanwhile, SIRT7 depletion can increase the sensitivity of breast cancer cells to doxorubicin (DOX). | Doxorubicin | sirtuin 7 | Homo sapiens |
| 3 | Xenograft model studies showed that stable silencing of SIRT7 inhibited tumor growth and enhanced tumor sensitivity to DOX. | Doxorubicin | sirtuin 7 | Homo sapiens |
| 4 | Taken together, our results showed that SIRT7 plays a critical role in breast cancer cell survival, migration, and tumor growth, and increased the efficiency of DOX treatment both in vitro and in vivo. | Doxorubicin | sirtuin 7 | Homo sapiens |