Pub. Date : 2014 Apr 1
PMID : 24536059
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SIRT7 belongs to the Sirtuin family of NAD-dependent enzymes, the members of which play diverse roles in aging, metabolism, and disease biology. | NAD | sirtuin 7 | Homo sapiens |
| 2 | SIRT7 associates with chromatin, where it catalyzes selective deacetylation of lysine 18 on histone H3 (H3K18), an emerging epigenetic biomarker of aggressive tumors and poor clinical outcome in patients with cancer. | Lysine | sirtuin 7 | Homo sapiens |