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| 2 | 7544437 | Functional regions of the mouse interleukin-10 receptor cytoplasmic domain. | Mol Cell Biol | 1995 Sep |
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| 3 | 7544789 | Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases. | J Biol Chem | 1995 Sep 1 |
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| 4 | 7637029 | Inhibition of protein phosphorylation modulates expression of the Jak family protein tyrosine kinases. | J Virol | 1995 Sep |
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| 5 | 8007943 | Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. | Mol Cell Biol | 1994 Jul |
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| 6 | 8013458 | Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells. | EMBO J | 1994 Jun 1 |
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| 7 | 8134389 | Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130. | Proc Natl Acad Sci U S A | 1994 Mar 15 |
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| 8 | 8657151 | Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins. | Mol Cell Biol | 1996 Apr |
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| 9 | 8703030 | Stat6 and Jak1 are common elements in platelet-derived growth factor and interleukin-4 signal transduction pathways in NIH 3T3 fibroblasts. | J Biol Chem | 1996 Sep 6 |
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| 10 | 9006890 | Constitutive activation of JAK1 in Src-transformed cells. | J Biol Chem | 1997 Jan 31 |
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| 11 | 9202205 | Alternative signaling mechanism of leukemia inhibitory factor responsiveness in a differentiating embryonal carcinoma cell. | Endocrinology | 1997 Jul |
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| 12 | 9218758 | Molecular role of TGF-beta, secreted from a new type of CD4+ suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice. | J Autoimmun | 1997 Jun |
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| 13 | 9238016 | Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1. | Proc Natl Acad Sci U S A | 1997 Aug 5 |
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| 14 | 9343427 | Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling. | Mol Cell Biol | 1997 Nov |
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| 15 | 9488432 | Erythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cells. | Mol Cell Biol | 1998 Mar |
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| 16 | 9510175 | Induction of Jak/STAT signaling by activation of the type 1 TNF receptor. | J Immunol | 1998 Mar 15 |
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| 17 | 10421786 | Activation of STAT5 by IL-4 relies on Janus kinase function but not on receptor tyrosine phosphorylation, and can contribute to both cell proliferation and gene regulation. | Int Immunol | 1999 Aug |
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| 18 | 10438942 | Mycobacterium avium infection of mouse macrophages inhibits IFN-gamma Janus kinase-STAT signaling and gene induction by down-regulation of the IFN-gamma receptor. | J Immunol | 1999 Aug 15 |
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| 19 | 10666420 | Interferon-gamma induces AT(2) receptor expression in fibroblasts by Jak/STAT pathway and interferon regulatory factor-1. | Circ Res | 2000 Feb 4 |
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| 20 | 10859312 | Protein-tyrosine phosphatase PTPepsilon C inhibits Jak-STAT signaling and differentiation induced by interleukin-6 and leukemia inhibitory factor in M1 leukemia cells. | J Biol Chem | 2000 Sep 8 |
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| 21 | 11071649 | Constitutive activation of STAT3 is associated with the acquisition of an interleukin 6-independent phenotype by murine plasmacytomas and hybridomas. | Blood | 2000 Nov 15 |
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| 22 | 11187900 | A transient dephosphorylation of JAK1 and JAK2 characterises the early-phase response of murine erythroleukemia cells to the differentiation inducer hexamethylenebisacetamide. | Leukemia | 2000 Dec |
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| 23 | 11278301 | Ultraviolet radiation inhibits interleukin-2-induced tyrosine phosphorylation and the activation of STAT5 in T lymphocytes. | J Biol Chem | 2001 Apr 20 |
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| 24 | 11481471 | An essential role of the JAK-STAT pathway in ischemic preconditioning. | Proc Natl Acad Sci U S A | 2001 Jul 31 |
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| 25 | 11866427 | The CrkL adapter protein is required for type I interferon-dependent gene transcription and activation of the small G-protein Rap1. | Biochem Biophys Res Commun | 2002 Mar 8 |
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| 26 | 12093291 | The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3. | Biochemistry | 2002 Jul 9 |
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| 27 | 12426308 | Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling. | J Biol Chem | 2003 Jan 31 |
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| 28 | 12589807 | Apoptosis induced by butyrate is independent of Jak/STAT signaling in a fibrosarcoma cell line. | Biochem Biophys Res Commun | 2003 Feb 21 |
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| 29 | 12738234 | Mechanism of cyclooxygenase-2 upregulation in late preconditioning. | J Mol Cell Cardiol | 2003 May |
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| 30 | 12842705 | STI571-resistant KT-1 cells are sensitive to interferon-alpha accompanied by the loss of T-cell protein tyrosine phosphatase and prolonged phosphorylation of Stat1. | Exp Hematol | 2003 Jul |
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| 31 | 15240680 | Adenosine acts through A2 receptors to inhibit IL-2-induced tyrosine phosphorylation of STAT5 in T lymphocytes: role of cyclic adenosine 3',5'-monophosphate and phosphatases. | J Immunol | 2004 Jul 15 |
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| 32 | 15659653 | The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities. | Mol Biol Cell | 2005 Apr |
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| 33 | 15671076 | Renal cells express a functional interleukin-15 receptor. | Nephrol Dial Transplant | 2005 Mar |
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| 34 | 15988755 | Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells. | J Cell Biochem | 2005 Oct 1 |
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| 35 | 16172266 | Role of the protein kinase C-epsilon-Raf-1-MEK-1/2-p44/42 MAPK signaling cascade in the activation of signal transducers and activators of transcription 1 and 3 and induction of cyclooxygenase-2 after ischemic preconditioning. | Circulation | 2005 Sep 27 |
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| 36 | 16417589 | Activation of JAK/STAT signalling in neurons following spinal cord injury in mice. | J Neurochem | 2006 Feb |
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| 37 | 16737695 | 15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells. | Exp Cell Res | 2006 Aug 1 |
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| 39 | 17803855 | [Budesonide attenuates airway remodeling and modules the expression of Janus protein tyrosine kinase 1, and signal transducers and activators of transcription 6 in asthma: an experiment with mice]. | Zhonghua Yi Xue Za Zhi | 2007 Jun 19 |
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| 40 | 17928529 | The ubiquitin-mediated degradation of Jak1 modulates osteoclastogenesis by limiting interferon-beta-induced inhibitory signaling. | Blood | 2008 Jan 15 |
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| 41 | 18362173 | Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia. | J Exp Med | 2008 Apr 14 |
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| 42 | 18718058 | [Regulatory effect of resveratrol on JAK1/STAT3 signal transduction pathway in leukemia]. | Zhongguo Shi Yan Xue Ye Xue Za Zhi | 2008 Aug |
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| 43 | 18995957 | Myricetin directly targets JAK1 to inhibit cell transformation. | Cancer Lett | 2009 Mar 8 |
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| 44 | 19181385 | GANP suppresses the arginine methyltransferase PRMT5 regulating IL-4-mediated STAT6-signaling to IgE production in B cells. | Mol Immunol | 2009 Mar |
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| 45 | 19561401 | Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression. | Exp Mol Med | 2009 Oct 31 |
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| 46 | 20060843 | Inhibition of nitric oxide production by quercetin in endotoxin/cytokine-stimulated microglia. | Life Sci | 2010 Feb 27 |
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| 47 | 20385788 | CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms. | Blood | 2010 Jun 24 |
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| 48 | 20711698 | Excess thyroid hormone inhibits embryonic neural stem/progenitor cells proliferation and maintenance through STAT3 signalling pathway. | Neurotox Res | 2011 Jul |
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| 49 | 21138870 | Dietary curcumin attenuates glioma growth in a syngeneic mouse model by inhibition of the JAK1,2/STAT3 signaling pathway. | Clin Cancer Res | 2010 Dec 1 |
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| 50 | 21604762 | Discovery of the macrocycle 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a potent Janus kinase 2/fms-like tyrosine kinase-3 (JAK2/FLT3) inhibitor for the treatment of myelofibrosis and lymphoma. | J Med Chem | 2011 Jul 14 |
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