Title : Constitutive activation of STAT3 is associated with the acquisition of an interleukin 6-independent phenotype by murine plasmacytomas and hybridomas.

Pub. Date : 2000 Nov 15

PMID : 11071649






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Further comparison of upstream signaling pathways revealed that JAK-1 was constitutively present in anti-phosphotyrosine immunoprecipitates of IL-6-independent cells; gp130 was constitutively phosphorylated in a subset of IL-6-independent plasmacytomas, whereas other IL-6-independent lines showed no detectable gp130 phosphorylation in the absence of exogenous IL-6. Phosphotyrosine Janus kinase 1 Mus musculus