Title : Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia.

Pub. Date : 2008 Apr 14

PMID : 18362173






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Three mutations that were studied promoted JAK1 gain of function and conferred interleukin (IL)-3-independent growth in Ba/F3 cells and/or IL-9-independent resistance to dexamethasone-induced apoptosis in T cell lymphoma BW5147 cells. Dexamethasone Janus kinase 1 Mus musculus