7-hydroxycoumarin






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1 1323288 ABA-induced 'lipid melting' and its reversal by umbelliferone in the plasmalemma of guard cell protoplasts: a breakthrough in plant hormone-receptor binding and hormone action. Biochem Biophys Res Commun 1992 Jul 31 1
2 1964228 The occurrence of beta-glucuronidase in erythrocyte inclusions. Acta Histochem Suppl 1990 1
3 3086205 Sublobular distribution of transferases and hydrolases associated with glucuronide, sulfate and glutathione conjugation in human liver. Hepatology 1986 May-Jun 1
4 6182644 Differential induction of UDP glucuronosyltransferase activities towards various substrates after polycyclic aromatic hydrocarbon administration to rats. Toxicol Lett 1982 Aug 1
5 6309775 Genetic polymorphisms for a phenobarbital-inducible cytochrome P-450 map to the Coh locus in mice. J Biol Chem 1983 Aug 25 2
6 6506757 Influence of cytochrome P-450 type on the pattern of conjugation of 7-hydroxycoumarin generated from 7-alkoxycoumarins. Xenobiotica 1984 Nov 1
7 7510710 Growth-inhibitory effects of coumarin (1,2-benzopyrone) and 7-hydroxycoumarin on human malignant cell lines in vitro. J Cancer Res Clin Oncol 1994 1
8 7726643 Induction of rat liver drug-metabolizing enzymes by tetrachloroethylene. Arch Environ Contam Toxicol 1995 Apr 1
9 7756103 CYP3A4 and CYP2A6 activities marked by the metabolism of lignocaine and coumarin in patients with liver and kidney diseases and epileptic patients. Br J Clin Pharmacol 1995 Jan 1
10 7856835 A continuous fluorescence-based assay for the human high-molecular-weight cytosolic phospholipase A2. Anal Biochem 1994 Oct 2
11 7953469 Effect of 1,2,4-trichlorodibenzo-p-dioxin on drug-metabolizing enzymes in the rat liver. Chemosphere 1994 Sep 3
12 8132699 Antibody-based approaches to coumarin analysis. J Cancer Res Clin Oncol 1994 2
13 8600835 Continuous, vesicle-based fluorimetric assays of 14- and 85-kDa phospholipases A2. Anal Biochem 1995 Nov 20 1
14 8641823 Matrix-induced liver cell aggregates (MILCA) for bioartificial liver use. Int J Artif Organs 1996 Jan 2
15 8642043 Suppression of the proliferation and migration of oncogenic ras-dependent cell lines, cultured in a three-dimensional collagen matrix, by flavonoid-structured molecules. J Cancer Res Clin Oncol 1996 4
16 8896890 Induction of cytochrome P450 2A6 expression in humans by the carcinogenic parasite infection, opisthorchiasis viverrini. Cancer Epidemiol Biomarkers Prev 1996 Oct 2
17 9022707 The lipase from Staphylococcus aureus. Expression in Escherichia coli, large-scale purification and comparison of substrate specificity to Staphylococcus hyicus lipase. Eur J Biochem 1996 Dec 15 1
18 9115999 Interfacial catalysis by human 85 kDa cytosolic phospholipase A2 on anionic vesicles in the scooting mode. Biochemistry 1997 Mar 18 1
19 9355936 Hepatitis A impairs the function of human hepatic CYP2A6 in vivo. Toxicology 1997 Dec 5 1
20 9373993 Blue light mediated photoreduction of the flavoprotein NADPH-cytochrome P450 reductase. A Förster-type energy transfer. Z Naturforsch C J Biosci 1997 Sep-Oct 2
21 9409631 A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin. Food Chem Toxicol 1997 Sep 1
22 9871718 An enantioselective fluorimetric assay for alcohol dehydrogenases using albumin-catalyzed beta-elimination of umbelliferone. Bioorg Med Chem Lett 1998 May 5 1
23 9918546 Biotransformation of coumarin by rodent and human cytochromes P-450: metabolic basis of tissue-selective toxicity in olfactory mucosa of rats and mice. J Pharmacol Exp Ther 1999 Feb 2
24 10376771 Genetic variation in the metabolism of coumarin in mouse liver. Pharmacogenetics 1999 Apr 1
25 10620357 Structure-function analysis of human cytochrome P450 3A4 using 7-alkoxycoumarins as active-site probes. Arch Biochem Biophys 2000 Jan 15 2
26 10781881 CYP2A6: a human coumarin 7-hydroxylase. Toxicology 2000 Apr 3 2
27 11566023 The role of cytochrome 2B1 substrate recognition site residues 115, 294, 297, 298, and 362 in the oxidation of steroids and 7-alkoxycoumarins. Arch Biochem Biophys 2001 Oct 1 1
28 11679177 Decrease of cyclin D1 in the human lung adenocarcinoma cell line A-427 by 7-hydroxycoumarin. Lung Cancer 2001 Nov 3
29 12185557 Phenotypic polymorphism of CYP2A6 activity in a Chinese population. Eur J Clin Pharmacol 2002 Aug 1
30 12388221 Is neuroprotective efficacy of nNOS inhibitor 7-NI dependent on ischemic intracellular pH? Am J Physiol Heart Circ Physiol 2003 Jan 1
31 12420755 Some coumarins and triphenylethene derivatives as inhibitors of human testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD type 3): further studies with tamoxifen on the rat testes microsomal enzyme. J Enzyme Inhib Med Chem 2002 Apr 1
32 12708602 Single copy of variant CYP2A6 alleles does not confer susceptibility to liver dysfunction in patients treated with coumarin. Int J Clin Pharmacol Ther 2003 Apr 1
33 12758156 Spectrofluorimetric analysis of 7-hydroxycoumarin binding to bovine phenol sulfotransferase. Biochim Biophys Acta 2003 May 30 4
34 13276338 Studies in detoxication. 67. The biosynthesis of the glucuronides of umbelliferone and 4-methylumbelliferone and their use in fluorimetric determination of beta-glucuronidase. Biochem J 1955 Dec 1
35 14738594 Study of inhibition of CYP2A6 by some drugs derived from quinoline. J Pharm Pharmacol 2003 Dec 1
36 15041069 Effects of chronic exposure to low-level cadmium on renal tubular function and CYP2A6-mediated coumarin metabolism in healthy human subjects. Toxicol Lett 2004 Mar 21 2
37 15044611 An active and water-soluble truncation mutant of the human UDP-glucuronosyltransferase 1A9. Mol Pharmacol 2004 Apr 1
38 15579072 Studies on coumarins and coumarin-related compounds to determine their therapeutic role in the treatment of cancer. Curr Pharm Des 2004 1
39 16289009 A direct fluorometric assay for tissue transglutaminase. Anal Biochem 2005 Dec 15 1
40 16329506 [Interaction between bovine serum albumin and umbelliferone with/without metal ions of Cu2+ or Zn2+]. Guang Pu Xue Yu Guang Pu Fen Xi 2005 Aug 1
41 17219461 Fluorogenic substrates for lipases, esterases, and acylases using a TIM-mechanism for signal release. Biotechnol J 2007 Feb 2
42 18452392 A fluorescence-based assay for monoacylglycerol lipase compatible with inhibitor screening. Assay Drug Dev Technol 2008 Jun 2
43 18642865 Latent fluorophores based on a self-immolative linker strategy and suitable for protease sensing. Bioconjug Chem 2008 Aug 1
44 18840518 Differences in simulated liver concentrations of toxic coumarin metabolites in rats and different human populations evaluated through physiologically based biokinetic (PBBK) modeling. Toxicol In Vitro 2008 Dec 1
45 19289114 Effects of umbelliferone in a murine model of allergic airway inflammation. Eur J Pharmacol 2009 May 1 3
46 19470355 Effect of umbelliferone (7-hydroxycoumarin, 7-HOC) on the enzymatic, edematogenic and necrotic activities of secretory phospholipase A2 (sPLA2) isolated from Crotalus durissus collilineatus venom. Toxicon 2009 Mar 15 3
47 19913056 Modulation of cytokine production by 7-hydroxycoumarin in vitro and its efficacy against influenza infection in mice. Antiviral Res 2010 Feb 2
48 20074593 Fluorogenic substrates for the screening assay of transketolase through beta-elimination of umbelliferone--Development, scope and limitations. J Biotechnol 2010 Feb 15 1
49 20534555 A fluorophore ligase for site-specific protein labeling inside living cells. Proc Natl Acad Sci U S A 2010 Jun 15 2
50 21362475 Thiomers: Inhibition of cytochrome P450 activity. Eur J Pharm Biopharm 2011 Aug 1