Title : Modulation of cytokine production by 7-hydroxycoumarin in vitro and its efficacy against influenza infection in mice.

Pub. Date : 2010 Feb

PMID : 19913056






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1 We previously demonstrated that 7-hydroxycoumarin (7HC) was effective in reducing proinflammatory cytokine production in lipopolysaccharide-exposed macrophage-like P388D1 cells and fever production by suppressing the increase in interleukin (IL)-1alpha production in an influenza virus-intranasal infection model in mice. 7-hydroxycoumarin interleukin 1 alpha Mus musculus
2 We previously demonstrated that 7-hydroxycoumarin (7HC) was effective in reducing proinflammatory cytokine production in lipopolysaccharide-exposed macrophage-like P388D1 cells and fever production by suppressing the increase in interleukin (IL)-1alpha production in an influenza virus-intranasal infection model in mice. 7-hydroxycoumarin interleukin 1 alpha Mus musculus