Title : Effects of chronic exposure to low-level cadmium on renal tubular function and CYP2A6-mediated coumarin metabolism in healthy human subjects.

Pub. Date : 2004 Mar 21

PMID : 15041069






2 Functional Relationships(s)
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1 In addition, urine Cd excretion of men and women showed a positive correlation (r = 0.46 to 0.54, P < 0.001) with urine 7-hydroxycoumarin (7-OHC) excretion which was used as a marker of liver cytochrome P450 2A6 (CYP2A6) enzyme activity. 7-hydroxycoumarin cytochrome P450 family 2 subfamily A member 6 Homo sapiens
2 In addition, urine Cd excretion of men and women showed a positive correlation (r = 0.46 to 0.54, P < 0.001) with urine 7-hydroxycoumarin (7-OHC) excretion which was used as a marker of liver cytochrome P450 2A6 (CYP2A6) enzyme activity. 7-hydroxycoumarin cytochrome P450 family 2 subfamily A member 6 Homo sapiens