| 151 |
16280038 | CYP17 and breast cancer: no overall effect, but what about interactions? | 2005 |
1 |
| 152 |
15220035 | Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study. | 2004 Jun 26 |
1 |
| 153 |
15466495 | CYP17 gene polymorphisms: prevalence and associations with hormone levels and related factors. a HuGE review. | 2004 Oct 15 |
3 |
| 154 |
15477877 | Serum sex steroid hormone levels and polymorphisms of CYP17 and SRD5A2: implication for prostate cancer risk. | 2004 |
1 |
| 155 |
15562394 | Functional characterization of mutant CYP17 genes isolated from a 17 alpha-hydroxylase/17,20-lyase-deficient patient. | 2004 Dec |
1 |
| 156 |
15625562 | Inhibition of CYP17 expression by adrenal androgens and transforming growth factor beta in adrenocortical cells. | 2004 |
1 |
| 157 |
12444089 | Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17. | 2003 Jan 31 |
1 |
| 158 |
12464252 | The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21. | 2003 Jan 1 |
1 |
| 159 |
12464253 | Ovine steroid 17alpha-hydroxylase cytochrome P450: characteristics of the hydroxylase and lyase activities of the adrenal cortex enzyme. | 2003 Jan 1 |
1 |
| 160 |
12493720 | Exogenous steroid substrate modifies the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estradiol production of human luteinized granulosa cells in vitro. | 2003 Jan |
1 |
| 161 |
12573489 | Molecular dynamics of substrate complexes with hamster cytochrome P450c17 (CYP17): mechanistic approach to understanding substrate binding and activities. | 2003 Feb 17 |
1 |
| 162 |
12631293 | Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor. Role of recombinant cytochrome b5 and P450 reductase. | 2003 Mar |
2 |
| 163 |
12701064 | A novel compound heterozygous mutation in the CYP17 (P450 17alpha-hydroxylase) gene leading to 17alpha-hydroxylase/17,20-lyase deficiency. | 2003 Apr |
1 |
| 164 |
12706306 | A complex heterozygous mutation of His373Leu and Asp487-Ser488-Phe489 deletion in human cytochrome P450c17 causes 17alpha-hydroxylase/17,20-lyase deficiency in three Chinese sisters. | 2003 Mar 28 |
1 |
| 165 |
12773039 | Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy. | 2003 Jun 5 |
1 |
| 166 |
12790800 | Inhibition of Src tyrosine kinase stimulates adrenal androgen production. | 2003 Jun |
1 |
| 167 |
12844345 | Activin signal transduction in the fetal rat adrenal gland and in human H295R cells. | 2003 Jul |
1 |
| 168 |
12915666 | The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway. | 2003 Aug |
1 |
| 169 |
12954495 | CYP17 gene promoter allelic variant is not associated with prostate cancer. | 2003 Jul-Aug |
1 |
| 170 |
14504283 | CYP17 mutation E305G causes isolated 17,20-lyase deficiency by selectively altering substrate binding. | 2003 Dec 5 |
4 |
| 171 |
14522586 | 5alpha-reduced C21 steroids are substrates for human cytochrome P450c17. | 2003 Oct 15 |
6 |
| 172 |
14561815 | A polymorphism in the CYP17 gene relates to the risk of recurrent pregnancy loss. | 2003 Nov |
2 |
| 173 |
15686129 | Cyp17 genetic polymorphism in prostate cancer and benign prostatic hyperplasia. | 2003 |
2 |
| 174 |
11869873 | Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. | 2002 Apr |
1 |
| 175 |
11880540 | The CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis. | 2002 Mar |
1 |
| 176 |
11911969 | CYP17 genetic polymorphism in endometrial cancer: are only steroids involved? | 2002 Jun 6 |
1 |
| 177 |
11955795 | Genetic modeling of estrogen metabolism as a risk factor of hormone-dependent disorders. | 2002 Apr 15 |
1 |
| 178 |
12020974 | Genetic modelling of the estrogen metabolism as a risk factor of hormone-dependent disorders. | 2002 May 20 |
1 |
| 179 |
12093119 | In vitro hCG and human recombinant FSH actions on testicular steroidogenesis in the toad Bufo arenarum. | 2002 May |
1 |
| 180 |
12423360 | Baboon cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17). | 2002 Nov |
2 |
| 181 |
12466376 | Differential inhibition of 17alpha-hydroxylase and 17,20-lyase activities by three novel missense CYP17 mutations identified in patients with P450c17 deficiency. | 2002 Dec |
1 |
| 182 |
12573809 | Androgen biosynthesis from cholesterol to DHEA. | 2002 Dec 30 |
1 |
| 183 |
15195127 | No association of the 5' promoter region polymorphism of CYP17 gene with prostate cancer risk. | 2002 |
1 |
| 184 |
11344930 | The genetics, pathophysiology, and management of human deficiencies of P450c17. | 2001 Mar |
2 |
| 185 |
11358812 | A polymorphism in CYP17 and endometrial cancer risk. | 2001 May 15 |
2 |
| 186 |
11463853 | NF-1C, Sp1, and Sp3 are essential for transcription of the human gene for P450c17 (steroid 17alpha-hydroxylase/17,20 lyase) in human adrenal NCI-H295A cells. | 2001 Aug |
1 |
| 187 |
10760835 | CYP17 promotor polymorphism and ovarian cancer risk. | 2000 May 1 |
1 |
| 188 |
10897051 | A polymorphism in the CYP17 gene is associated with prostate cancer risk. | 2000 Aug 1 |
2 |
| 189 |
10963624 | Molecular epidemiology of genetic polymorphisms in estrogen metabolizing enzymes in human breast cancer. | 2000 |
1 |
| 190 |
11036113 | CYP17 promoter polymorphism and breast cancer in Australian women under age forty years. | 2000 Oct 18 |
5 |
| 191 |
11059764 | Increased risk of prostate cancer and benign prostatic hyperplasia associated with a CYP17 gene polymorphism with a gene dosage effect. | 2000 Oct 15 |
2 |
| 192 |
11117668 | The function and roles of P450c17 in androgen excess states. | 2000 |
2 |
| 193 |
11142420 | Steroid metabolism gene CYP17 polymorphism and the development of breast cancer. | 2000 Dec |
1 |
| 194 |
9892022 | P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b5. | 1999 Jan |
1 |
| 195 |
10070957 | The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer. | 1999 Mar 1 |
2 |
| 196 |
10407219 | Sexual dimorphism in the maturation of the pituitary-gonadal axis, assessed by GnRH agonist challenge. | 1999 Jul |
1 |
| 197 |
9452426 | Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer. | 1998 Feb 6 |
3 |
| 198 |
9648052 | Typical hormonal profiles are accompanied by increased immunoreactivity of theca folliculi steroid 17 alpha-hydroxylase P450 in polycystic ovary syndrome. | 1998 May |
2 |
| 199 |
9703423 | Identification of a novel splicing mutation and 1-bp deletion in the 17alpha-hydroxylase gene of Japanese patients with 17alpha-hydroxylase deficiency. | 1998 Jun |
1 |
| 200 |
9755461 | [The regulation of steroidogenesis by 17 alpha-hydroxylase/17,20-lyase (P450c17)]. | 1998 Jul |
3 |