17 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 30885648 | Design and synthesis of novel steroidal imidazoles as dual inhibitors of AR/CYP17 for the treatment of prostate cancer. | 2019 Oct | 1 |
2 | 29283561 | Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202. | 2018 Feb 6 | 1 |
3 | 29718108 | The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro. | 2018 Oct 1 | 1 |
4 | 27566228 | Structural insights into the function of steroidogenic cytochrome P450 17A1. | 2017 Feb 5 | 1 |
5 | 28373265 | Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1. | 2017 Jun | 2 |
6 | 27002602 | Enantioselective endocrine disrupting effects of omeprazole studied in the H295R cell assay and by molecular modeling. | 2016 Aug | 1 |
7 | 25650406 | Partial deficiency of 17α-hydroxylase/17,20-lyase caused by a novel missense mutation in the canonical cytochrome heme-interacting motif. | 2015 May | 1 |
8 | 24328388 | Resonance Raman spectroscopy reveals that substrate structure selectively impacts the heme-bound diatomic ligands of CYP17. | 2014 Jan 14 | 1 |
9 | 24971814 | Novel oxazolinyl derivatives of pregna-5,17(20)-diene as 17α-hydroxylase/17,20-lyase (CYP17A1) inhibitors. | 2014 Oct | 1 |
10 | 21446712 | Why human cytochrome P450c21 is a progesterone 21-hydroxylase. | 2011 May 17 | 2 |
11 | 19454579 | Steroid 17alpha-hydroxylase deficiency: functional characterization of four mutations (A174E, V178D, R440C, L465P) in the CYP17A1 gene. | 2009 Aug | 1 |
12 | 16176874 | Novel mutation of the CYP17 gene in two unrelated patients with combined 17alpha-hydroxylase/17,20-lyase deficiency: demonstration of absent enzyme activity by expressing the mutant CYP17 gene and by three-dimensional modeling. | 2005 Nov | 5 |
13 | 12773039 | Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy. | 2003 Jun 5 | 1 |
14 | 11243732 | Mutation of proline 409 to arginine in the meander region of cytochrome p450c17 causes severe 17 alpha-hydroxylase deficiency. | 2001 Mar | 1 |
15 | 9703423 | Identification of a novel splicing mutation and 1-bp deletion in the 17alpha-hydroxylase gene of Japanese patients with 17alpha-hydroxylase deficiency. | 1998 Jun | 1 |
16 | 9177409 | A 5'-splice site mutation in the cytochrome P450 steroid 17alpha-hydroxylase gene in 17alpha-hydroxylase deficiency. | 1997 Jun | 1 |
17 | 22217842 | Molecular basis of 17α-hydroxylase/17,20-lyase deficiency. | 1992 Dec | 2 |