Abiraterone Acetate

cytochrome P450 family 17 subfamily A member 1 ; Homo sapiens







97 Article(s)
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1 33495313 Abiraterone Acetate Induces CREB1 Phosphorylation and Enhances the Function of the CBP-p300 Complex, Leading to Resistance in Prostate Cancer Cells. 2021 Apr 1 1
2 34041015 Synergistic Effect of Statins and Abiraterone Acetate on the Growth Inhibition of Neuroblastoma via Targeting Androgen Receptor. 2021 1
3 34333840 Warning against second-generation antiandrogen for metastatic castration sensitive prostate cancer. 2021 Nov 1
4 34493283 The effects of selected inhibitors on human fetal adrenal steroidogenesis differs under basal and ACTH-stimulated conditions. 2021 Sep 8 2
5 31611636 Exposure-response analyses of abiraterone and its metabolites in real-world patients with metastatic castration-resistant prostate cancer. 2020 Jun 1
6 32045360 Abiraterone acetate treatment lowers 11-oxygenated androgens. 2020 Apr 2
7 32581567 Association Between CYP17A1, CYB5A Polymorphisms and Efficacy of Abiraterone Acetate/Prednisone Treatment in Castration-Resistant Prostate Cancer Patients. 2020 2
8 32911627 Adherence Measures for Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Abiraterone Acetate plus Prednisone: Results of a Prospective, Cluster-Randomized Trial. 2020 Sep 8 1
9 33004739 CYP17 inhibitors improve the prognosis of metastatic castration-resistant prostate cancer patients: A meta-analysis of published trials. 2020 Sep 1
10 30427533 A phase 2 trial of abiraterone acetate without glucocorticoids for men with metastatic castration-resistant prostate cancer. 2019 Feb 15 1
11 30537624 An LC-MS/MS method for quantification of abiraterone, its active metabolites D(4)-abiraterone (D4A) and 5α-abiraterone, and their inactive glucuronide derivatives. 2019 Jan 1 2
12 30770950 Abiraterone acetate exerts a cytotoxic effect in human prostate cancer cell lines. 2019 Jun 2
13 28715929 Molecular interactions of bisphenols and analogs with glucocorticoid biosynthetic pathway enzymes: an in silico approach. 2018 Jan 1
14 29438990 Nuclear Receptor LRH-1 Functions to Promote Castration-Resistant Growth of Prostate Cancer via Its Promotion of Intratumoral Androgen Biosynthesis. 2018 May 1 1
15 29541468 Baseline neutrophil-to-lymphocyte ratio predicts the prognosis of castration-resistant prostate cancer treated with abiraterone acetate. 2018 Apr 1
16 30029732 Dehydroepiandrosterone (DHEA)-SO4 Depot and Castration-Resistant Prostate Cancer. 2018 1
17 26862015 Steroid 17-hydroxylase and 17,20-lyase deficiencies, genetic and pharmacologic. 2017 Jan 2
18 27753628 Study of cases of abiraterone discontinuation due to toxicity in pre-chemotherapy after 1 year's experience. 2017 Dec 1
19 28819727 Abiraterone Acetate: A Review in Metastatic Castration-Resistant Prostrate Cancer. 2017 Sep 2
20 28852974 Low dose versus standard dose of corticosteroids in the management of adverse events of special interest from abiraterone acetate: data from a literature-based meta-analysis. 2017 Aug 29 1
21 29110971 The effects of enzalutamide and abiraterone on skeletal related events and bone radiological progression free survival in castration resistant prostate cancer patients: An indirect comparison of randomized controlled trials. 2017 Dec 1
22 26965562 Low Incidence of Corticosteroid-associated Adverse Events on Long-term Exposure to Low-dose Prednisone Given with Abiraterone Acetate to Patients with Metastatic Castration-resistant Prostate Cancer. 2016 Sep 1
23 26971191 A single-center experience with abiraterone as treatment for metastatic castration-resistant prostate cancer. 2016 Jul 1
24 26971992 Incidence and relative risk of adverse events of special interest in patients with castration resistant prostate cancer treated with CYP-17 inhibitors: A meta-analysis of published trials. 2016 May 1
25 27007943 Cytochrome P450 17A1 Inhibitor Abiraterone Acetate Counteracts the Heat Shock Protein 27's Cell Survival Properties in Prostate Cancer Cells. 2016 1
26 27278777 Association of early PSA decline and time to PSA progression in abiraterone acetate-treated metastatic castration-resistant prostate cancer; a post-hoc analysis of Japanese phase 2 trials. 2016 Jun 8 1
27 27358844 Feasibility of abiraterone acetate treatment in patients with metastatic castration-resistant prostate cancer and atrial fibrillation. 2016 Jun 1
28 27482286 CYP17 inhibitors in prostate cancer: latest evidence and clinical potential. 2016 Jul 2
29 27504016 In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity. 2016 Oct 1
30 27544566 How I do it: Prescribing abiraterone acetate for metastatic castration resistant prostate cancer. 2016 Aug 1
31 27561266 High prevalence of potential drug-drug interactions in patients with castration-resistant prostate cancer treated with abiraterone acetate. 2016 Nov 1
32 27748439 Targeting of CYP17A1 Lyase by VT-464 Inhibits Adrenal and Intratumoral Androgen Biosynthesis and Tumor Growth of Castration Resistant Prostate Cancer. 2016 Oct 17 1
33 25560485 CYP17A1 inhibitors in castration-resistant prostate cancer. 2015 Mar 1
34 25813901 A HPLC-fluorescence method for the quantification of abiraterone in plasma from patients with metastatic castration-resistant prostate cancer. 2015 May 1 1
35 25936418 Pharmacokinetics, pharmacodynamics and clinical efficacy of abiraterone acetate for treating metastatic castration-resistant prostate cancer. 2015 Jun 1
36 26025264 The development of abiraterone acetate for castration-resistant prostate cancer. 2015 Jun 1
37 26032458 Mechanisms of drug resistance that target the androgen axis in castration resistant prostate cancer (CRPC). 2015 Sep 1
38 26082421 Role of chemotherapy in the treatment of metastatic castration-resistant prostate cancer patients who have progressed after abiraterone acetate. 2015 Sep 1
39 26134919 Metastatic castration-resistant prostate cancer: targeting the mechanisms of resistance to abiraterone acetate and enzalutamide. 2015 2
40 26814148 Mechanisms of resistance in castration-resistant prostate cancer (CRPC). 2015 Jun 1
41 24276076 CYP17 inhibitors--abiraterone, C17,20-lyase inhibitors and multi-targeting agents. 2014 Jan 1
42 24284787 Differential response to abiraterone acetate and di-n-butyl phthalate in an androgen-sensitive human fetal testis xenograft bioassay. 2014 Mar 1
43 24508512 A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone. 2014 Sep 2
44 24759590 Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer. 2014 May-Jun 1
45 24775307 Highly-selective 4-(1,2,3-triazole)-based P450c17a 17,20-lyase inhibitors. 2014 Jun 1 1
46 24780050 Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency. 2014 Aug 1
47 24793632 [Abiraterone acetate (AA): current guidelines of prescription of abiraterone]. 2014 Apr 1
48 24890318 Targeting the androgen receptor in prostate cancer. 2014 Jul 1
49 25047002 Inhibition of the androgen receptor by mineralocorticoids at levels physiologically achieved in serum in patients treated with abiraterone acetate. 2014 Sep 1
50 25111736 Retreatment of men with metastatic castrate-resistant prostate cancer with abiraterone. 2014 Oct 1