Title : Nuclear Receptor LRH-1 Functions to Promote Castration-Resistant Growth of Prostate Cancer via Its Promotion of Intratumoral Androgen Biosynthesis.

Pub. Date : 2018 May 1

PMID : 29438990






1 Functional Relationships(s)
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1 Targeting of steroidogenic enzymes (e.g., abiraterone acetate targeting CYP17A1) has been developed as a novel therapeutic strategy against metastatic castration-resistant prostate cancer (CRPC). Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens