Title : Low Incidence of Corticosteroid-associated Adverse Events on Long-term Exposure to Low-dose Prednisone Given with Abiraterone Acetate to Patients with Metastatic Castration-resistant Prostate Cancer.

Pub. Date : 2016 Sep

PMID : 26965562






1 Functional Relationships(s)
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1 BACKGROUND: Abiraterone acetate (AA) is the prodrug of abiraterone, which inhibits CYP17A1 and testosterone synthesis and prolongs the survival of patients with metastatic castration-resistant prostate cancer (mCRPC). Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens