Title : Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer.

Pub. Date : 2014 May-Jun

PMID : 24759590






1 Functional Relationships(s)
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1 Abiraterone acetate was developed as an irreversible inhibitor of the dual functional cytochrome P450 enzyme CYP17 with activity as a 17alpha-hydroxylase and 17,20-lyase. Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens